SCHEMBL13569412

SCHEMBL13569412

C=CC(=O)OC(COC(=O)C(=C)C)COc1ccc(-c2ccc(N(c3ccc(C)cc3)c3ccc(CCc4ccccc4)cc3)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 3/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
GAA P10253 1/20 0.36
FFAR4 Q5NUL3 2/20 0.35
PPARG P37231 2/20 0.35
PPARA Q07869 1/20 0.35
THRB P10828 2/20 0.34
TRPM8 Q7Z2W7 1/20 0.34
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
ALDH1A1 P00352 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CNR2 P34972 1/20 0.33
MMP12 P39900 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13569419 0.95 THRB (0.36) FFAR1MEN1KMT2AFFAR4PPARG
SCHEMBL13569406 0.94 MAPT (0.35) FFAR4PPARGPPARATHRBTRPM8
SCHEMBL13569404 0.92 AR (0.34) MEN1KMT2AALDH1A1
SCHEMBL13569417 0.90 MAPT (0.37) PPARGPPARATHRBLMNA
SCHEMBL13569398 0.90 THRB (0.37) THRBLMNA
SCHEMBL13569415 0.90 CTDSP1 (0.35) KMT2APPARGPPARATHRBTRPM8
SCHEMBL13569405 0.89 MAPT (0.37) THRBLMNA
SCHEMBL13569401 0.87 LTB4R2 (0.37) PPARGPPARATHRBL3MBTL1
SCHEMBL13569414 0.87 THRB (0.37) GAATHRB
SCHEMBL13569407 0.87 TSHR (0.36) MEN1KMT2AGAATHRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7629094-B2 Electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2009-12-08 US disclosed