SCHEMBL13569404

SCHEMBL13569404

C=CC(=O)OC(COC(=O)C(=C)C)COc1ccc(-c2ccc(N(c3ccc(C)cc3)c3ccc(C)cc3)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.34
HTT P42858 4/20 0.33
POLB P06746 2/20 0.33
APEX1 P27695 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
MAPT P10636 3/20 0.32
TSHR P16473 2/20 0.32
MAPK1 P28482 1/20 0.32
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MAOB P27338 1/20 0.31
HPGD P15428 2/20 0.31
ALDH1A1 P00352 2/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
ACACB O00763 1/20 0.30
ACACA Q13085 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13569406 0.96 MAPT (0.35) ARHTTPOLBAPEX1TDP1
SCHEMBL13569411 0.93 CHKA (0.34) ARHTTPOLBAPEX1TDP1
SCHEMBL6014306 0.92 MAOB (0.39) ARHTTPOLBAPEX1TDP1
SCHEMBL6014302 0.92 MAOB (0.39) ARHTTPOLBAPEX1TDP1
SCHEMBL13569415 0.92 CTDSP1 (0.35) TDP1SMN1; SMN2KMT2AMAPTMAPK1
SCHEMBL13569412 0.92 FFAR1 (0.37) MEN1KMT2AALDH1A1
SCHEMBL13569417 0.92 MAPT (0.37) ARHTTPOLBAPEX1TDP1
SCHEMBL13569398 0.92 THRB (0.37) ARHTTPOLBAPEX1TDP1
SCHEMBL13569403 0.92 TSHR (0.36) ARHTTPOLBAPEX1TDP1
SCHEMBL13569405 0.91 MAPT (0.37) ARHTTPOLBAPEX1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8669030-B2 Electrophotographic photoreceptor, and image forming method and apparatus using the same RICOH COMPANY, LIMITED (JP) 2014-03-11 US disclosed
US-8669030-B2 Electrophotographic photoreceptor, and image forming method and apparatus using the same RICOH COMPANY, LIMITED (JP) 2014-03-11 US disclosed
US-7629094-B2 Electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2009-12-08 US disclosed
US-20080138725-A1 Electrophotographic photoreceptor, and image forming method and apparatus using the same RICOH COMPANY LIMITED (JP) 2008-06-12 US disclosed
US-20080138725-A1 Electrophotographic photoreceptor, and image forming method and apparatus using the same RICOH COMPANY LIMITED (JP) 2008-06-12 US disclosed