SCHEMBL13569433

SCHEMBL13569433

C=CC(=O)OC(COC(=O)C(=C)C)COc1ccc(-c2ccc(N(c3cccc(C)c3)c3cccc(C)c3)cc2C)c(C)c1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13569438 0.91 ESR1 (0.32) POLB
SCHEMBL13569399 0.89 LTB4R2 (0.36) KDM4EPOLB
SCHEMBL13569431 0.89 KDM4E (0.30) KDM4EPOLB
SCHEMBL13569401 0.87 LTB4R2 (0.37) KDM4EPOLB
SCHEMBL13569429 0.82 PDK2 (0.30)
SCHEMBL13569397 0.81 AR (0.32) POLB
SCHEMBL13569435 0.81 MCHR1 (0.34)
SCHEMBL13569434 0.81 MAOA (0.32)
SCHEMBL13569437 0.81 PDK2 (0.30)
SCHEMBL13569446 0.81 PDK2 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7629094-B2 Electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2009-12-08 US disclosed