SCHEMBL13569397

SCHEMBL13569397

C=CC(=O)OC(COC(=O)C(=C)C)COc1ccc(-c2ccc(N(c3ccc(C)c(C)c3)c3ccc(C)c(C)c3)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
POLB P06746 2/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13778854 0.91 NPC1 (0.34) ARNPC1RAB9APOLBTDP1
SCHEMBL13569404 0.91 AR (0.34) ARPOLBAPEX1HTTTDP1
SCHEMBL13569438 0.90 ESR1 (0.32) ARPOLBAPEX1TDP1
SCHEMBL13569411 0.90 CHKA (0.34) ARNPC1POLBAPEX1HTT
SCHEMBL13569399 0.89 LTB4R2 (0.36) ARPOLBAPEX1HTTTDP1
SCHEMBL13569417 0.89 MAPT (0.37) ARNPC1RAB9APOLBAPEX1
SCHEMBL13569403 0.89 TSHR (0.36) ARPOLBAPEX1HTTTDP1
SCHEMBL13569398 0.89 THRB (0.37) ARNPC1RAB9APOLBAPEX1
SCHEMBL13569405 0.88 MAPT (0.37) ARNPC1RAB9APOLBAPEX1
SCHEMBL13569401 0.88 LTB4R2 (0.37) NPC1RAB9APOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7629094-B2 Electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2009-12-08 US disclosed