SCHEMBL13569441

SCHEMBL13569441

Cc1ccc(N(C)c2ccc(CCc3ccccc3)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.55
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
TAAR1 Q96RJ0 2/20 0.47
CNR2 P34972 3/20 0.46
AOC3 Q16853 2/20 0.46
CHKA P35790 1/20 0.44
SIGMAR1 Q99720 1/20 0.44
LMNA P02545 1/20 0.44
POLB P06746 1/20 0.44
KCNH2 Q12809 1/20 0.44
CYP1A2 P05177 1/20 0.43
CYP2A6 P11509 1/20 0.43
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
ALDH1A1 P00352 1/20 0.43
TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28318832 0.88 CYP2C19 (0.55) CYP2C19TDP1CNR2CHKALMNA
SCHEMBL5937231 0.87 CHKA (0.55) TAAR1AOC3CHKASIGMAR1LMNA
SCHEMBL12900156 0.87 SIGMAR1 (0.53) CYP2C19AOC3CHKASIGMAR1KCNH2
SCHEMBL14647590 0.86 CYP2C19 (0.57) CYP2C19TDP1L3MBTL1TAAR1CNR2
SCHEMBL12506243 0.85 TDP1 (0.59) CYP2C19TDP1L3MBTL1TAAR1LMNA
SCHEMBL3022199 0.85 TDP1 (0.59) CYP2C19TDP1L3MBTL1TAAR1LMNA
SCHEMBL21987885 0.84 ALDH1A1 (0.50) CYP2C19TDP1CNR2CHKALMNA
SCHEMBL3050460 0.83 TSHR (0.55) CYP2C19TDP1CHKALMNAALDH1A1
Ammonia Solution, Strong SCHEMBL10723459 0.83 TDP1 (0.57) CYP2C19TDP1L3MBTL1TAAR1LMNA
Benzene SCHEMBL14537402 0.83 TSHR (0.55) CYP2C19TDP1CHKALMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7629094-B2 Electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2009-12-08 US disclosed