Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | CCR6 | P51684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9317348 | 0.87 | ALDH1A1 (0.63) | PTGS2CYP19A1CYP11B2ALDH1A1MAPT | |
| SCHEMBL6140273 | 0.85 | CYP19A1 (0.55) | PTGS2CYP19A1CYP11B2ALDH1A1MAPT | |
| SCHEMBL7570019 | 0.85 | CYP19A1 (0.55) | PTGS2CYP19A1CYP11B2ALDH1A1MAPT | |
| SCHEMBL6032733 | 0.85 | CYP19A1 (0.55) | PTGS2CYP19A1CYP11B2ALDH1A1MAPT | |
| SCHEMBL14018365 | 0.85 | CYP19A1 (0.55) | PTGS2CYP19A1CYP11B2ALDH1A1MAPT | |
| SCHEMBL133557 | 0.85 | CYP19A1 (0.55) | PTGS2CYP19A1CYP11B2ALDH1A1MAPT | |
| SCHEMBL10128938 | 0.85 | CYP19A1 (0.55) | PTGS2CYP19A1CYP11B2ALDH1A1MAPT | |
| SCHEMBL13980016 | 0.84 | ALDH1A1 (0.56) | PTGS2CYP19A1CYP11B2ALDH1A1MAPT | |
| SCHEMBL14044715 | 0.83 | ESR1 (0.55) | PTGS2CYP19A1CYP11B2ALDH1A1MAPT | |
| SCHEMBL4310935 | 0.83 | ESR1 (0.55) | PTGS2CYP19A1CYP11B2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629094-B2 | Electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the electrophotographic photoreceptor | RICOH COMPANY, LTD. (JP) | 2009-12-08 | — | — | US | disclosed |
| US-7629094-B2 | Electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the electrophotographic photoreceptor | RICOH COMPANY, LTD. (JP) | 2009-12-08 | — | — | US | disclosed |
| EP-1674940-B1 | Electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the electrophotographic photoreceptor | RICOH KK (JP) | 2008-11-26 | — | — | EP | disclosed |