SCHEMBL9317348

SCHEMBL9317348

CN(C)c1ccc(C=C(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.63
MAPT P10636 7/20 0.63
RAB9A P51151 5/20 0.63
L3MBTL1 Q9Y468 2/20 0.63
MAPK1 P28482 1/20 0.63
KMT2A Q03164 7/20 0.59
LMNA P02545 1/20 0.59
GAA P10253 1/20 0.59
RELA Q04206 1/20 0.57
MEN1 O00255 4/20 0.56
PTGS2 P35354 2/20 0.54
NPC1 O15118 3/20 0.53
HPGD P15428 2/20 0.53
CYP19A1 P11511 1/20 0.53
CYP11B2 P19099 1/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
PKM P14618 1/20 0.50
ESR1 P03372 1/20 0.50
GFER P55789 1/20 0.50
CYP2D6 P10635 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13980016 0.93 ALDH1A1 (0.56) ALDH1A1MAPTRAB9AL3MBTL1MAPK1
SCHEMBL9718468 0.92 ESR1 (0.60) ALDH1A1MAPTRAB9AL3MBTL1MAPK1
SCHEMBL13569445 0.87 PTGS2 (0.53) ALDH1A1MAPTRAB9AL3MBTL1MAPK1
SCHEMBL16946576 0.87 CYP19A1 (0.72) ALDH1A1MAPTRAB9AL3MBTL1MAPK1
SCHEMBL13930392 0.85 MAPT (0.50) ALDH1A1MAPTRAB9AL3MBTL1MAPK1
SCHEMBL13930398 0.85 MAPT (0.50) ALDH1A1MAPTRAB9AL3MBTL1MAPK1
SCHEMBL2210133 0.84 CYP19A1 (0.57) ALDH1A1MAPTRAB9AL3MBTL1MAPK1
SCHEMBL2121142 0.83 CYP19A1 (0.71) ALDH1A1MAPTPTGS2HPGDCYP19A1
SCHEMBL14570726 0.83 PTGS1 (0.65) ALDH1A1MAPTRAB9AL3MBTL1MAPK1
SCHEMBL25909565 0.83 PTGS1 (0.65) ALDH1A1MAPTRAB9AL3MBTL1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-58198425-A None JP disclosed
US-8017807-B2 Tetrahydroxy compound, method for preparing the tetrahydroxy compound, and photoreceptor using the tetrahydroxy compound RICOH COMPANY LIMITED (JP) 2011-09-13 US disclosed
EP-1898262-B1 Electrophotographic photoconductor and method for producing the same, image forming apparatus, and process cartridge RICOH KK (JP) 2009-12-30 EP disclosed
EP-1898262-A1 Electrophotographic photoconductor and method for producing the same, image forming apparatus, and process cartridge Ricoh Company, Ltd. (JP) 2008-03-12 EP disclosed
US-20070128530-A1 TETRAHYDROXY COMPOUND, METHOD FOR PREPARING THE TETRAHYDROXY COMPOUND, AND PHOTORECEPTOR USING THE TETRAHYDROXY COMPOUND RICOH COMPANY, LTD. (JP) 2007-06-07 US disclosed
US-5292602-A Charge generating layer FUGI ELECTRIC CO., LTD. (JP) 1994-03-08 US disclosed
US-5292608-A Charge generating layer FUGI ELECTRIC CO., LTD. (JP) 1994-03-08 US disclosed
US-5286590-A Bisazo photoconductor for electrophotography FUJI ELECTRIC CO., LTD. (JP) 1994-02-15 US disclosed
US-5275898-A Contains thiophene ring FUJI ELECTRIC CO., LTD. (JP) 1994-01-04 US disclosed
US-5266430-A Bisazo gharge generating agent FUJI ELECTRIC CO., LTD. (JP) 1993-11-30 US disclosed
US-4971876-A TETRAKISAZO COMPOUNDS FUJI ELECTRIC CO., LTD. (JP) 1990-11-20 US disclosed
US-4956250-A MULTILAYER CHARGE GENERATING AZULENIUM COMPOUND FOR LIGHT SENSITIVE ELEMENTS FUJI ELECTRIC CO., LTD. (JP) 1990-09-11 US disclosed
US-4935323-A THIOPHENE OR THIAZOLE-CONTAINING BISAZO CHARGE GENERATING COMPOUND FUJI ELECTRIC CO., LTD. (JP) 1990-06-19 US disclosed
US-4929525-A SENSITIVE, DURABLE FUJI ELECTRIC CO., LTD. 1990-05-29 US disclosed
US-4917981-A Photosensitive member for electrophotography FUJI ELECTRIC CO., LTD. (JP) 1990-04-17 US disclosed
US-4892949-A ORGANIC PHOTOCONDUCTORS RICOH COMPANY, LTD. (JP) 1990-01-09 US disclosed
US-4877703-A Photoconductor for electrophotography having a squarylium charge generating dye FUJI ELECTRIC CO., LTD. (JP) 1989-10-31 US disclosed
US-4871636-A CHARGE GENERATING COMPOUND FUJI ELECTRIC CO., LTD. (JP) 1989-10-03 US disclosed
US-4859556-A MULTILAYER; ELECTROCONDUCTIVE SUPPORT WITH PHOTOSENSITIVE MATERIAL RICOH COMPANY, LTD. (JP) 1989-08-22 US disclosed
JP-S58198425-A ALPHA-PHENYLSTILBENE DERIVATIVE AND PREPARATION THEREOF RICOH CO LTD 1983-11-18 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070128530-A1 TETRAHYDROXY COMPOUND, METHOD FOR PREPARING THE TETRAHYDROXY COMPOUND, AND PHOTORECEPTOR USING THE TETRAHYDROXY COMPOUND ALDH1A2, SLC9B2, SLC18A2 ALDH1A1 485/4885MAPT 2694/4885RAB9A 394/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.