Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.45 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | WNT3 | P56703 | 1/20 | 0.37 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.37 |
| ▸ | RHOA | P61586 | 7/20 | 0.36 |
| ▸ | RHOC | P08134 | 2/20 | 0.36 |
| ▸ | TACR2 | P21452 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13569702 | 0.95 | LMNA (0.41) | KCNH2CACNA1ILMNAALDH1A1CCR2 | |
| SCHEMBL4282723 | 0.90 | KCNH2 (0.56) | KCNH2CACNA1ILMNAALDH1A1CCR2 | |
| SCHEMBL4280512 | 0.85 | KCNH2 (0.50) | KCNH2CACNA1ILMNAALDH1A1CCR2 | |
| SCHEMBL4284054 | 0.84 | KCNH2 (0.60) | KCNH2CACNA1ICCR2 | |
| SCHEMBL4284052 | 0.84 | KCNH2 (0.60) | KCNH2CACNA1ICCR2 | |
| SCHEMBL13569689 | 0.83 | KCNH2 (0.49) | KCNH2CACNA1IALDH1A1CCR2RHOA | |
| SCHEMBL13569688 | 0.81 | KCNH2 (0.49) | KCNH2CACNA1ICCR2TACR1 | |
| SCHEMBL4279833 | 0.81 | KCNH2 (0.58) | KCNH2CACNA1IALDH1A1CCR2TACR2 | |
| SCHEMBL20056370 | 0.81 | KCNH2 (0.39) | KCNH2CACNA1IALDH1A1CCR2TACR1 | |
| SCHEMBL19113254 | 0.80 | KCNH2 (0.61) | KCNH2CACNA1I |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146540-A1 | N-PIPERIDINYL ACETAMIDE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | NEUROMED PHARMACEUTICALS LTD (CA) | 2009-12-10 | — | — | WO | disclosed |