Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.41 |
| ▸ | CACNA1I | Q9P0X4 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 2/20 | 0.35 |
| ▸ | WNT3 | P56703 | 1/20 | 0.35 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13569698 | 0.95 | KCNH2 (0.45) | LMNAKCNH2CACNA1IALDH1A1CCR2 | |
| SCHEMBL4280512 | 0.91 | KCNH2 (0.50) | LMNAKCNH2CACNA1IALDH1A1CACNA1G | |
| SCHEMBL20056370 | 0.86 | KCNH2 (0.39) | KCNH2CACNA1IALDH1A1CACNA1GCACNA1H | |
| SCHEMBL4278565 | 0.85 | KCNH2 (0.54) | KCNH2CACNA1IALDH1A1CACNA1GCACNA1H | |
| SCHEMBL4278560 | 0.85 | KCNH2 (0.54) | KCNH2CACNA1IALDH1A1CACNA1GCACNA1H | |
| SCHEMBL4282723 | 0.85 | KCNH2 (0.56) | LMNAKCNH2CACNA1IALDH1A1CCR2 | |
| SCHEMBL13569802 | 0.85 | NPY5R (0.42) | LMNAKCNH2CACNA1ICACNA1GCACNA1H | |
| SCHEMBL13569811 | 0.84 | KCNH2 (0.42) | LMNAKCNH2CACNA1IALDH1A1CACNA1G | |
| SCHEMBL19113351 | 0.84 | KCNH2 (0.43) | LMNAKCNH2CACNA1IALDH1A1CACNA1G | |
| SCHEMBL13569753 | 0.83 | KCNH2 (0.47) | KCNH2CACNA1ICACNA1GCACNA1HCCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146540-A1 | N-PIPERIDINYL ACETAMIDE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | NEUROMED PHARMACEUTICALS LTD (CA) | 2009-12-10 | — | — | WO | disclosed |