Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.42 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.42 |
| ▸ | WNT3 | P56703 | 1/20 | 0.41 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | RHOA | P61586 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13569758 | 0.93 | KDM4E (0.41) | NPY5RKCNH2CACNA1IWNT3SFRP1 | |
| SCHEMBL4271313 | 0.91 | KCNH2 (0.52) | NPY5RKCNH2CACNA1IWNT3SFRP1 | |
| SCHEMBL13569700 | 0.87 | KCNH2 (0.45) | NPY5RKCNH2CACNA1IWNT3SFRP1 | |
| SCHEMBL13569753 | 0.87 | KCNH2 (0.47) | NPY5RKCNH2CACNA1ICACNA1GCACNA1H | |
| SCHEMBL13569811 | 0.86 | KCNH2 (0.42) | KCNH2CACNA1ICACNA1GCACNA1HLMNA | |
| SCHEMBL13569702 | 0.85 | LMNA (0.41) | NPY5RKCNH2CACNA1IWNT3SFRP1 | |
| SCHEMBL4277715 | 0.84 | KCNH2 (0.59) | NPY5RKCNH2CACNA1IWNT3SFRP1 | |
| SCHEMBL4282719 | 0.84 | KCNH2 (0.50) | NPY5RKCNH2CACNA1ICACNA1GCACNA1H | |
| SCHEMBL19112606 | 0.83 | CACNA1I (0.42) | NPY5RKCNH2CACNA1IWNT3SFRP1 | |
| SCHEMBL20056370 | 0.83 | KCNH2 (0.39) | NPY5RKCNH2CACNA1ICACNA1GCACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146540-A1 | N-PIPERIDINYL ACETAMIDE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | NEUROMED PHARMACEUTICALS LTD (CA) | 2009-12-10 | — | — | WO | disclosed |