Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 4/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.43 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16509728 | 1.00 | SLC6A3 (0.56) | SLC6A3SMN1; SMN2NPSR1TDP1ALDH1A1 | |
| SCHEMBL10094741 | 0.72 | SMN1; SMN2 (0.56) | SLC6A3SMN1; SMN2TDP1ALDH1A1MAPT | |
| SCHEMBL17227576 | 0.69 | SMN1; SMN2 (0.42) | SLC6A3SMN1; SMN2NPSR1TDP1MAPT | |
| SCHEMBL29783446 | 0.69 | MAPT (0.56) | SMN1; SMN2NPSR1ALDH1A1MAPTLMNA | |
| SCHEMBL20670512 | 0.69 | SMN1; SMN2 (0.44) | SLC6A3SMN1; SMN2NPSR1TDP1MAPT | |
| SCHEMBL10153401 | 0.68 | SMN1; SMN2 (0.41) | SLC6A3SMN1; SMN2NPSR1TDP1MAPT | |
| SCHEMBL12905011 | 0.68 | MAPT (0.41) | SLC6A3SMN1; SMN2MAPTCYP2C9CYP2C19 | |
| SCHEMBL19002786 | 0.68 | ALDH1A1 (0.53) | ALDH1A1MAPTTSHRLMNAHTT | |
| SCHEMBL2069336 | 0.68 | NPC1 (0.64) | SLC6A3SMN1; SMN2TDP1ALDH1A1MAPT | |
| SCHEMBL12888984 | 0.67 | MAPT (0.40) | SLC6A3SMN1; SMN2MAPTCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009153721-A1 | NICOTINAMIDE DERIVATIVES | PFIZER LIMITED (GB) | 2009-12-23 | — | — | WO | disclosed |