Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 20/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.78 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.78 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.78 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4289739 | 0.88 | CYP26A1 (1.00) | CYP26A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4278684 | 0.83 | CYP26A1 (1.00) | CYP26A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4284567 | 0.79 | CYP26A1 (1.00) | CYP26A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4283372 | 0.79 | CYP26A1 (1.00) | CYP26A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4280032 | 0.79 | CYP26A1 (1.00) | CYP26A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4276106 | 0.79 | CYP26A1 (1.00) | CYP26A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4282150 | 0.78 | CYP26A1 (1.00) | CYP26A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4280477 | 0.78 | GABBR2 (0.49) | CYP26A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4283358 | 0.77 | CYP26A1 (1.00) | CYP26A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4284772 | 0.76 | CYP26A1 (1.00) | CYP26A1CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009153566-A1 | CYP26 INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2009-12-23 | — | — | WO | disclosed |