Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GCGR | P47871 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4511779 | 0.90 | MAPT (0.48) | HSD17B10CDC7DBF4CYP4F2CYP4A11 | |
| SCHEMBL13574329 | 0.88 | HSD17B10 (0.57) | HSD17B10CDC7DBF4SMN1; SMN2ALDH1A1 | |
| SCHEMBL14252657 | 0.82 | ALDH1A1 (0.53) | HSD17B10SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL20806332 | 0.81 | KDM4E (0.49) | HSD17B10SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL4805155 | 0.80 | CNR1 (0.47) | HSD17B10CDC7DBF4SMN1; SMN2ALDH1A1 | |
| SCHEMBL4681530 | 0.78 | TARBP2 (0.54) | HSD17B10CYP4F2CYP4A11SMN1; SMN2ALDH1A1 | |
| SCHEMBL4515129 | 0.78 | HSD17B10 (0.58) | HSD17B10CDC7DBF4SMN1; SMN2ALDH1A1 | |
| SCHEMBL4514685 | 0.76 | HSD17B10 (0.43) | HSD17B10CDC7DBF4SMN1; SMN2KDM4E | |
| SCHEMBL20806339 | 0.76 | TSHR (0.58) | HSD17B10CDC7DBF4CYP4F2CYP4A11 | |
| SCHEMBL4509242 | 0.76 | MAPT (0.47) | HSD17B10CDC7DBF4SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009153569-A2 | CB1 RECEPTOR MODULATORS | 7TM PHARMA A/S (DK) | 2009-12-23 | — | — | WO | disclosed |