Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 7/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.43 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4511779 | 0.85 | MAPT (0.48) | HSD17B10MAPTSMN1; SMN2NPC1POLB | |
| SCHEMBL4805155 | 0.83 | CNR1 (0.47) | HSD17B10MAPTSMN1; SMN2NPC1POLB | |
| SCHEMBL4515129 | 0.82 | HSD17B10 (0.58) | HSD17B10MAPTSMN1; SMN2NPC1POLB | |
| SCHEMBL4504078 | 0.79 | HSD17B10 (0.42) | HSD17B10MAPTSMN1; SMN2NPC1POLB | |
| SCHEMBL4513493 | 0.78 | CNR1 (0.45) | SMN1; SMN2NPC1POLBRAB9ACNR1 | |
| SCHEMBL3879970 | 0.78 | OPRL1 (0.43) | SMN1; SMN2NPC1POLBRAB9ACNR1 | |
| SCHEMBL4677074 | 0.78 | SLC2A1 (0.48) | MAPTSMN1; SMN2NPC1TSHRRAB9A | |
| SCHEMBL4509242 | 0.77 | MAPT (0.47) | HSD17B10MAPTSMN1; SMN2NPC1POLB | |
| SCHEMBL13574337 | 0.76 | HSD17B10 (0.47) | HSD17B10MAPTSMN1; SMN2NPC1POLB | |
| SCHEMBL3952036 | 0.74 | CNR1 (0.43) | CNR1CNR2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203699-A1 | AMINOMETHYLPYRIDINE DERIVATIVES, METHOD FOR PREPARING SAME AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203699-A1 | AMINOMETHYLPYRIDINE DERIVATIVES, METHOD FOR PREPARING SAME AND THERAPEUTIC USE THEREOF | TPMT, QDPR, HNMT | HSD17B10 4108/4885MAPT 1642/4885SMN1; SMN2 771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.