SCHEMBL1357556

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1356468	0.89	SIGMAR1 (1.00)	SIGMAR1ABL1ENPP2ALDH1A1
	SCHEMBL1356838	0.89	SIGMAR1 (1.00)	SIGMAR1ABL1ENPP2ALDH1A1
	SCHEMBL1356195	0.88	SIGMAR1 (0.66)	SIGMAR1ABL1
	SCHEMBL1356701	0.87	SIGMAR1 (0.61)	SIGMAR1ENPP2ALDH1A1GAANPSR1
	SCHEMBL1356999	0.87	SIGMAR1 (0.80)	SIGMAR1ABL1ENPP2ALDH1A1POLB
	Oxalic Acid SCHEMBL1357630	0.84	SIGMAR1 (0.58)	SIGMAR1ENPP2ALDH1A1POLBTSHR
	SCHEMBL1354868	0.84	SIGMAR1 (0.57)	SIGMAR1ENPP2ALDH1A1TSHREGFR
	SCHEMBL1356927	0.82	SIGMAR1 (0.69)	SIGMAR1ABL1ENPP2POLBL3MBTL1
	SCHEMBL4656581	0.82	SIGMAR1 (0.69)	SIGMAR1ABL1
	SCHEMBL1357278	0.82	SIGMAR1 (0.78)	SIGMAR1ABL1ENPP2ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.