Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | ACR | P10323 | 1/20 | 0.34 |
| ▸ | CTRC | Q99895 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13578473 | 0.84 | EGFR (0.41) | MAPTKMT2ASMN1; SMN2THRBNPC1 | |
| SCHEMBL13578706 | 0.83 | HTT (0.31) | MAPTSMN1; SMN2KDM4EHTTALDH1A1 | |
| SCHEMBL8956431 | 0.82 | PARP10 (0.42) | MAPTKMT2ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL126667 | 0.80 | PARP10 (0.45) | MAPTKMT2ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL16114028 | 0.80 | KMT2A (0.50) | MAPTKMT2ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL9871665 | 0.76 | KMT2A (0.56) | MAPTKMT2ASMN1; SMN2THRBNPC1 | |
| SCHEMBL13222378 | 0.76 | HSD17B10 (0.50) | MAPTKMT2ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL394648 | 0.74 | — | — | |
| SCHEMBL7746430 | 0.74 | MAPT (0.47) | MAPTKMT2ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL9872218 | 0.72 | ESR1 (0.55) | MAPTKMT2ASMN1; SMN2NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629051-B2 | Optical film containing fluorinated photopolymerization initiator, antireflective film, polarizing plate and image display unit including same | FUJIFILM CORPORATION (JP) | 2009-12-08 | — | — | US | disclosed |