Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | RNASEL | Q05823 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | STS | P08842 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872065 | 0.92 | ALDH1A1 (0.53) | ESR1LMNACYP1A2TSHRCYP2C19 | |
| SCHEMBL9872852 | 0.86 | TSHR (0.37) | ESR1LMNACYP1A2TSHRCYP2C19 | |
| SCHEMBL124262 | 0.86 | CA12 (0.50) | ESR1LMNACYP1A2TSHRCYP2C19 | |
| SCHEMBL9873018 | 0.85 | TSHR (0.42) | ESR1LMNACYP1A2TSHRCYP2C19 | |
| SCHEMBL13873051 | 0.84 | TDP1 (0.40) | ESR1LMNACYP1A2TSHRCYP2C19 | |
| SCHEMBL990934 | 0.80 | RAB9A (0.56) | LMNACYP1A2CYP2C19CYP2D6SMN1; SMN2 | |
| SCHEMBL13996230 | 0.80 | ESR1 (0.77) | ESR1LMNACYP1A2TSHRCYP2C19 | |
| SCHEMBL5028687 | 0.80 | ESR1 (0.77) | ESR1LMNACYP1A2TSHRCYP2C19 | |
| SCHEMBL9871106 | 0.80 | ESR1 (0.57) | ESR1LMNATSHRMAPK1SMN1; SMN2 | |
| SCHEMBL7746430 | 0.79 | MAPT (0.47) | LMNATSHRSMN1; SMN2HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5064959-A | Photoinitiators | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-11-12 | — | — | US | disclosed |