Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 2/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 12/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 5/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 5/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.38 |
| ▸ | HK1 | P19367 | 2/20 | 0.38 |
| ▸ | BCL2 | P10415 | 3/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.37 |
| ▸ | BCL2A1 | Q16548 | 3/20 | 0.37 |
| ▸ | BCL2L2 | Q92843 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | G6PD | P11413 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13578711 | 0.86 | BRAF (0.38) | BRAFMCL1HKDC1KEAP1NFE2L2 | |
| SCHEMBL13578713 | 0.84 | BRAF (0.43) | BRAFMCL1HKDC1KEAP1NFE2L2 | |
| SCHEMBL13578769 | 0.84 | L3MBTL1 (0.55) | BRAFMCL1KEAP1NFE2L2KDM4E | |
| SCHEMBL13509762 | 0.75 | BRAF (0.60) | BRAFSTAT3MCL1HKDC1KEAP1 | |
| SCHEMBL13509708 | 0.73 | STAT3 (0.67) | BRAFSTAT3MCL1HKDC1KEAP1 | |
| SCHEMBL13511835 | 0.72 | BRAF (0.59) | BRAFSTAT3MCL1HKDC1KEAP1 | |
| SCHEMBL13509704 | 0.72 | STAT3 (0.66) | BRAFSTAT3MCL1HKDC1KEAP1 | |
| SCHEMBL13509710 | 0.71 | STAT3 (0.58) | BRAFSTAT3MCL1HKDC1KEAP1 | |
| SCHEMBL13509718 | 0.69 | STAT3 (0.65) | BRAFSTAT3MCL1HKDC1KEAP1 | |
| SCHEMBL13509706 | 0.68 | STAT3 (0.61) | BRAFSTAT3MCL1HKDC1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009149192-A1 | STAT3 INHIBITORS | BAYLOR COLLEGE OF MEDICINE (US) | 2009-12-10 | — | — | WO | disclosed |