Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HTR1A | P08908 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | HTR7 | P34969 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | HTR6 | P50406 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | XBP1 | P17861 | 1/20 | 0.53 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13578727 | 0.84 | BRAF (0.47) | L3MBTL1MAPTHPGDKDM4EMEN1 | |
| SCHEMBL13578711 | 0.82 | BRAF (0.38) | MAPTHPGDKDM4EMEN1ALDH1A1 | |
| SCHEMBL13510093 | 0.79 | MEN1 (0.63) | L3MBTL1MAPTHPGDKDM4EMEN1 | |
| SCHEMBL13578713 | 0.78 | BRAF (0.43) | L3MBTL1MAPTHPGDKDM4EMEN1 | |
| SCHEMBL13509985 | 0.78 | HTT (0.77) | L3MBTL1MAPTHPGDKDM4EMEN1 | |
| SCHEMBL13509979 | 0.77 | KDM4E (0.76) | L3MBTL1MAPTHPGDKDM4EMEN1 | |
| SCHEMBL13509989 | 0.76 | ALDH1A1 (0.68) | L3MBTL1MAPTHPGDKDM4EMEN1 | |
| SCHEMBL13510004 | 0.74 | MEN1 (0.74) | L3MBTL1MAPTHPGDKDM4EMEN1 | |
| SCHEMBL13509981 | 0.74 | KDM4E (0.71) | L3MBTL1MAPTHPGDKDM4EMEN1 | |
| SCHEMBL13510072 | 0.73 | MAPT (0.73) | L3MBTL1MAPTHPGDKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009149192-A1 | STAT3 INHIBITORS | BAYLOR COLLEGE OF MEDICINE (US) | 2009-12-10 | — | — | WO | disclosed |