Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I3 | Q14994 | 2/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12713402 | 0.75 | TDP1 (0.66) | KMT2AMEN1SMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL3766697 | 0.67 | RAB9A (0.73) | NR1I3CYP1A2CYP2C9RAB9AKMT2A | |
| SCHEMBL25798633 | 0.66 | RAB9A (0.53) | NR1I3RAB9AKMT2AMEN1GAA | |
| SCHEMBL17904147 | 0.66 | NR1I3 (0.68) | NR1I3CYP1A2CYP3A4CYP2C9CYP2B6 | |
| SCHEMBL29712523 | 0.66 | RAB9A (0.66) | NR1I3CYP1A2CYP2C9RAB9AKMT2A | |
| SCHEMBL883671 | 0.66 | RAB9A (0.66) | NR1I3CYP1A2CYP2C9RAB9AKMT2A | |
| SCHEMBL4546934 | 0.66 | RAB9A (0.66) | NR1I3CYP1A2CYP2C9RAB9AKMT2A | |
| SCHEMBL4546968 | 0.66 | RAB9A (0.70) | NR1I3CYP1A2CYP2C9RAB9AKMT2A | |
| SCHEMBL16542825 | 0.65 | NR1I3 (0.67) | NR1I3RAB9AKMT2AMEN1GAA | |
| SCHEMBL20081044 | 0.65 | BCL2 (0.53) | CYP1A2RAB9AKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009144584-A1 | ANTI-LIGANDS MOLECULES AND BIOLOGICAL APPLICATIONS | MITOLOGICS (FR) | 2009-12-03 | — | — | WO | disclosed |