Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.66 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | APEX1 | P27695 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | UCK2 | Q9BZX2 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13580089 | 0.77 | POLB (0.50) | TDP1CTDSP1MEN1KMT2ARXFP1 | |
| SCHEMBL13580091 | 0.75 | NR1I3 (0.68) | TDP1MEN1KMT2ARXFP1HTT | |
| SCHEMBL13253112 | 0.70 | KMT2A (0.81) | TDP1CTDSP1MEN1KMT2ARXFP1 | |
| SCHEMBL12869999 | 0.69 | TDP1 (0.64) | TDP1CTDSP1MEN1KMT2ARXFP1 | |
| SCHEMBL28407262 | 0.68 | POLB (0.54) | TDP1CTDSP1MEN1KMT2ARXFP1 | |
| SCHEMBL15528643 | 0.66 | F2 (0.61) | TDP1MEN1KMT2APOLBKDM4E | |
| SCHEMBL14543307 | 0.65 | NLRP3 (0.70) | MEN1KMT2AKDM4ESMN1; SMN2MAPT | |
| SCHEMBL13832144 | 0.64 | ALDH1A1 (0.67) | TDP1LMNAPOLBKDM4EHTT | |
| SCHEMBL2404195 | 0.64 | MAPT (0.56) | TDP1MEN1KMT2ALMNAPOLB | |
| SCHEMBL11221078 | 0.64 | SMN1; SMN2 (0.64) | MEN1KMT2AHTTL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9657031-B2 | Ant-ligands molecules and biological applications | UNIVERSITE DE VERSAILLES-SAINT-QUENTIN-EN-YVELINES (FR) | 2017-05-23 | — | — | US | disclosed |
| US-9657031-B2 | Ant-ligands molecules and biological applications | UNIVERSITE DE VERSAILLES-SAINT-QUENTIN-EN-YVELINES (FR) | 2017-05-23 | — | — | US | disclosed |
| US-20140350033-A1 | ANT-LIGANDS MOLECULES AND BIOLOGICAL APPLICATIONS | MITOLOGICS (FR) | 2014-11-27 | — | — | US | disclosed |
| US-20140350033-A1 | ANT-LIGANDS MOLECULES AND BIOLOGICAL APPLICATIONS | MITOLOGICS (FR) | 2014-11-27 | — | — | US | disclosed |
| US-8809346-B2 | ANT-ligands molecules and biological applications | UNIVERSITE DE VERSAILLES-SAINT-QUENTIN-EN-YVELINES (FR) | 2014-08-19 | — | — | US | disclosed |
| US-8809346-B2 | ANT-ligands molecules and biological applications | UNIVERSITE DE VERSAILLES-SAINT-QUENTIN-EN-YVELINES (FR) | 2014-08-19 | — | — | US | disclosed |
| US-20110086865-A1 | ANT-LIGANDS MOLECULES AND BIOLOGICAL APPLICATIONS | MITOLOGICS (FR) | 2011-04-14 | — | — | US | disclosed |
| US-20110086865-A1 | ANT-LIGANDS MOLECULES AND BIOLOGICAL APPLICATIONS | MITOLOGICS (FR) | 2011-04-14 | — | — | US | disclosed |
| WO-2009144584-A1 | ANTI-LIGANDS MOLECULES AND BIOLOGICAL APPLICATIONS | MITOLOGICS (FR) | 2009-12-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140350033-A1 | ANT-LIGANDS MOLECULES AND BIOLOGICAL APPLICATIONS | CXCR3, ACKR3, CCR3 | TDP1 4210/4885CTDSP1 2072/4885MEN1 2079/4885 |
| US-20110086865-A1 | ANT-LIGANDS MOLECULES AND BIOLOGICAL APPLICATIONS | CXCR3, ACKR3, CCR3 | TDP1 4489/4885CTDSP1 2616/4885MEN1 1906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.