Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | DPP4 | P27487 | 7/20 | 0.60 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.59 |
| ▸ | CTSL | P07711 | 1/20 | 0.54 |
| ▸ | CTSB | P07858 | 1/20 | 0.54 |
| ▸ | CTSK | P43235 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | CCR1 | P32246 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8785544 | 0.89 | ALDH1A1 (0.60) | ALDH1A1GAADPP4DPP7KCNH2 | |
| SCHEMBL3948461 | 0.83 | ALDH1A1 (0.85) | ALDH1A1GAADPP4DPP7KCNH2 | |
| SCHEMBL3948456 | 0.83 | ALDH1A1 (0.85) | ALDH1A1GAADPP4DPP7KCNH2 | |
| SCHEMBL381922 | 0.83 | ALDH1A1 (0.85) | ALDH1A1GAADPP4DPP7KCNH2 | |
| SCHEMBL25935100 | 0.82 | ALDH1A1 (0.57) | ALDH1A1GAADPP4DPP7KCNH2 | |
| SCHEMBL1424064 | 0.82 | EPHX1 (0.84) | ALDH1A1GAADPP4DPP7KCNH2 | |
| SCHEMBL8393719 | 0.82 | EPHX1 (0.84) | ALDH1A1GAADPP4DPP7KCNH2 | |
| Hydrochloric Acid SCHEMBL28135182 | 0.82 | ALDH1A1 (0.83) | ALDH1A1GAADPP4DPP7KCNH2 | |
| SCHEMBL2681634 | 0.81 | ALDH1A1 (0.72) | ALDH1A1GAADPP4DPP7KCNH2 | |
| SCHEMBL856165 | 0.81 | ALDH1A1 (0.72) | ALDH1A1GAADPP4DPP7KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009071519-A9 | OXADIAZOLE DERIVATIVES AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS | GLAXO GROUP LIMITED (GB) | 2009-12-03 | — | — | WO | disclosed |
| WO-2009071519-A1 | OXADIAZOLE DERIVATIVES AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS | GLAXO GROUP LIMITED (GB) | 2009-06-11 | — | — | WO | disclosed |