SCHEMBL13580324

Cc1cc(-c2cc(C)c(/N=N/C=C3C=C(C(C)(C)C)C(=O)C(C(C)(C)C)=C3)cc2C)c(C)cc1/N=N/C=C1C=C(C(C)(C)C)C(=O)C(C(C)(C)C)=C1

nearest known ligand 0.35

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	NPC1	O15118	1/20	0.35

▸	KMT2A	Q03164	1/20	0.35

▸	ATM	Q13315	1/20	0.35

▸	GPR35	Q9HC97	1/20	0.35

▸	SMN1; SMN2	Q16637	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL13580861	0.89	—	—
SCHEMBL13580350	0.88	NPC1 (0.33)	NPC1KMT2AATMGPR35
SCHEMBL13580341	0.88	NPC1 (0.33)	NPC1KMT2AATMGPR35
SCHEMBL13580738	0.88	NPC1 (0.32)	NPC1KMT2AATMGPR35
SCHEMBL13580735	0.85	NPC1 (0.31)	NPC1KMT2AATMGPR35
SCHEMBL13580355	0.84	SMN1; SMN2 (0.34)	NPC1KMT2AATMGPR35SMN1; SMN2
SCHEMBL13580329	0.82	KMT2A (0.39)	NPC1KMT2AATMGPR35SMN1; SMN2
SCHEMBL13580328	0.80	SENP2 (0.37)	NPC1KMT2AATMGPR35SMN1; SMN2
SCHEMBL13580416	0.77	SMN1; SMN2 (0.44)	NPC1KMT2AATMGPR35SMN1; SMN2
SCHEMBL13580325	0.77	ATM (0.36)	NPC1KMT2AATMGPR35SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20090317733-A1	Quinone Compound, Electrophotographic Photoconductor and Electrophotographic Apparatus	FUJI ELECTRIC DEVICE TECHNOLOGY CO., LTD. (JP)	2009-12-24	—	—	US	disclosed
US-20090317733-A1	Quinone Compound, Electrophotographic Photoconductor and Electrophotographic Apparatus	FUJI ELECTRIC DEVICE TECHNOLOGY CO., LTD. (JP)	2009-12-24	—	—	US	disclosed