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SCHEMBL13580355

SCHEMBL13580355

Cc1cc(-c2cc(C)c(/N=N/C=C3C=C(C(C)(C)C)C(=O)C(C(C)(C)C)=C3)cc2-c2ccccc2)c(-c2ccccc2)cc1/N=N/C=C1C=C(C(C)(C)C)C(=O)C(C(C)(C)C)=C1

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 2/20 0.34
▸ NPC1 O15118 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ ATM Q13315 1/20 0.33
▸ GPR35 Q9HC97 1/20 0.33
▸ LMNA P02545 1/20 0.31
▸ MCOLN3 Q8TDD5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13580401 0.84 SMN1; SMN2 (0.33) SMN1; SMN2NPC1KMT2AATMGPR35
SCHEMBL13580324 0.84 NPC1 (0.35) SMN1; SMN2NPC1KMT2AATMGPR35
SCHEMBL13580357 0.83 SMN1; SMN2 (0.36) SMN1; SMN2NPC1KMT2AATMGPR35
SCHEMBL13580738 0.83 NPC1 (0.32) NPC1KMT2AATMGPR35
SCHEMBL13580348 0.81 NPC1 (0.34) SMN1; SMN2NPC1KMT2AATMGPR35
SCHEMBL13580421 0.81 SMN1; SMN2 (0.36) SMN1; SMN2NPC1KMT2AATMGPR35
SCHEMBL13580350 0.81 NPC1 (0.33) NPC1KMT2AATMGPR35
SCHEMBL13580329 0.80 KMT2A (0.39) SMN1; SMN2NPC1KMT2AATMGPR35
SCHEMBL13580394 0.79 PTGS2 (0.35) SMN1; SMN2NPC1KMT2AATMGPR35
SCHEMBL13580397 0.79 CASP3 (0.35) SMN1; SMN2NPC1KMT2AATMGPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090317733-A1 Quinone Compound, Electrophotographic Photoconductor and Electrophotographic Apparatus FUJI ELECTRIC DEVICE TECHNOLOGY CO., LTD. (JP) 2009-12-24 — — US disclosed
US-20090317733-A1 Quinone Compound, Electrophotographic Photoconductor and Electrophotographic Apparatus FUJI ELECTRIC DEVICE TECHNOLOGY CO., LTD. (JP) 2009-12-24 — — US disclosed
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