Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 15/20 | 0.44 |
| ▸ | LPL | P06858 | 4/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | LIPC | P11150 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1410402 | 0.81 | FFAR4 (0.47) | FFAR4CYP2C9CYP2C19 | |
| SCHEMBL1410821 | 0.77 | NOTUM (0.62) | — | |
| SCHEMBL12210016 | 0.76 | LIPG (0.47) | LIPGLPLFFAR4LIPC | |
| SCHEMBL12210096 | 0.76 | LIPG (0.61) | LIPGLPLFFAR4LIPC | |
| SCHEMBL1410458 | 0.75 | LIPG (0.46) | LIPGLPLFFAR4LIPC | |
| SCHEMBL1409542 | 0.75 | LIPG (0.47) | LIPGLPLFFAR4LIPCALDH1A1 | |
| SCHEMBL1410556 | 0.75 | LIPG (0.60) | LIPGLPLFFAR4LIPC | |
| SCHEMBL1410343 | 0.73 | LMNA (0.55) | LIPGLPLMAPTMEN1ALDH1A1 | |
| SCHEMBL1410455 | 0.72 | LIPG (0.43) | LIPGLPLFFAR4LIPCMAPT | |
| SCHEMBL1410555 | 0.72 | LIPG (0.56) | LIPGLPLLIPCLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009145286-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-12-03 | — | — | WO | disclosed |