SCHEMBL1358262

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10306734	0.90	ENPP3 (0.50)	LTA4HESR1ESR2SMN1; SMN2KCNH2
	SCHEMBL1359614	0.89	ESR1 (0.55)	HTTESR1ESR2KCNH2ALDH1A1
	SCHEMBL1358420	0.89	ESR1 (0.54)	LTA4HESR1ESR2PSMB1PSMB5
	SCHEMBL1358193	0.89	ESR1 (0.54)	LTA4HESR1ESR2PSMB1PSMB5
	SCHEMBL1358542	0.88	ENPP3 (0.51)	LTA4HESR1ESR2PSMB1PSMB5
	SCHEMBL10306634	0.87	ESR1 (0.52)	LTA4HESR1ESR2PSMB1PSMB5
	SCHEMBL3115415	0.86	LTA4H (0.52)	HTTLTA4HESR1ESR2NPC1
	SCHEMBL1357972	0.82	HTT (0.56)	HTTLTA4HESR1ESR2NPC1
	SCHEMBL1360621	0.80	HTT (0.53)	HTTLTA4HESR1ESR2NPC1
	SCHEMBL5421491	0.79	HTT (0.52)	HTTLTA4HESR1ESR2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.