SCHEMBL1358397

SCHEMBL1358397

Cc1c(C(=O)c2cnn(C)c2O)ccc(S(C)(=O)=O)c1OC(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1358388 0.86 MAPT (0.31)
SCHEMBL1358053 0.83
SCHEMBL12602531 0.82 SMN1; SMN2 (0.32)
SCHEMBL8177016 0.82 PRKDC (0.36)
SCHEMBL1359001 0.81
SCHEMBL1032962 0.81 CCNB2 (0.34)
SCHEMBL645624 0.81 NR3C1 (0.31)
SCHEMBL3767515 0.79 ALDH1A1 (0.31)
SCHEMBL8183678 0.79 FGFR1 (0.30)
SCHEMBL9076487 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1963274-B1 BENZOYLPYRAZOLE COMPOUNDS AND HERBICIDES CONTAINING THEM ISHIHARA SANGYO KAISHA (JP) 2015-04-29 EP disclosed
US-8466088-B2 Herbicidal compositions containing benzoylpyrazole compounds ISHIHARA SANGYO KAISHA, LTD. (JP) 2013-06-18 US disclosed
EP-2546240-A1 Benzoylpyrazole compounds and herbicides containing them ISHIHARA SANGYO KAISHA, LTD. (JP) 2013-01-16 EP disclosed
US-20110282070-A1 BENZOYLPYRAZOLE COMPOUNDS AND HERBICIDES CONTAINING THEM ISHIHARA SANGYO KAISHA, LTD. (JP) 2011-11-17 US disclosed
US-8030498-B2 Benzoylpyrazole compounds and herbicides containing them ISHIHARA SANGYO KAISHA, LTD. (JP) 2011-10-04 US disclosed
US-20100099563-A1 HERBICIDAL COMPOSITIONS CONTAINING BENZOYLPYRAZOLE COMPOUNDS ISHIHARA SANGYO KAISHA, LTD. (JP) 2010-04-22 US disclosed
US-20090286683-A1 BENZOYLPYRAZOLE COMPOUNDS AND HERBICIDES CONTAINING THEM ISHIHARA SANGYO KAISHA, LTD. (JP) 2009-11-19 US disclosed
EP-2106697-A1 HERBICIDAL COMPOSITIONS CONTAINING BENZOYLPYRAZOLE COMPOUNDS ISHIHARA SANGYO KAISHA, LTD. (JP) 2009-10-07 EP disclosed