Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20386687 | 0.81 | BACE1 (0.32) | BACE1 | |
| SCHEMBL9732940 | 0.80 | MAPT (0.35) | BACE1MAPTHPGD | |
| SCHEMBL13584746 | 0.76 | SHBG (0.35) | HPGD | |
| SCHEMBL4133567 | 0.76 | MEN1 (0.37) | BACE1MAPTHPGD | |
| SCHEMBL18553121 | 0.75 | BACE1 (0.34) | BACE1 | |
| SCHEMBL28556535 | 0.74 | BACE1 (0.31) | BACE1MAPTHPGD | |
| SCHEMBL9237098 | 0.73 | BACE1 (0.34) | BACE1 | |
| SCHEMBL2750402 | 0.72 | BACE1 (0.47) | BACE1MAPTHPGD | |
| SCHEMBL4685089 | 0.72 | BACE1 (0.36) | BACE1MAPTHPGD | |
| SCHEMBL18393602 | 0.72 | CA2 (0.38) | BACE1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722656-B2 | Cephalosporins useful as antibacterial agents | ZOETIS LLC (US) | 2014-05-13 | — | — | US | disclosed |
| US-8722656-B2 | Cephalosporins useful as antibacterial agents | ZOETIS LLC (US) | 2014-05-13 | — | — | US | disclosed |
| US-8722656-B2 | Cephalosporins useful as antibacterial agents | ZOETIS LLC (US) | 2014-05-13 | — | — | US | disclosed |
| US-20120283237-A1 | NOVEL CEPHALOSPORINS USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2012-11-08 | — | — | US | disclosed |
| US-20120283237-A1 | NOVEL CEPHALOSPORINS USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2012-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120283237-A1 | NOVEL CEPHALOSPORINS USEFUL AS ANTIBACTERIAL AGENTS | CIAPIN1, CLSPN, MRPL21 | BACE1 2591/4885MAPT 4673/4885HPGD 1809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.