Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18114633 | 0.82 | TSHR (0.33) | ALDH1A1TSHRTHRB | |
| SCHEMBL28330737 | 0.81 | TSHR (0.41) | ALDH1A1TSHRTHRB | |
| SCHEMBL22371482 | 0.80 | TSHR (0.41) | ALDH1A1TSHRTHRB | |
| SCHEMBL1014718 | 0.79 | ALDH1A1 (0.40) | ALDH1A1TSHRTHRB | |
| SCHEMBL1019849 | 0.78 | TSHR (0.39) | ALDH1A1TSHRTHRB | |
| Hydrogen Sulfide SCHEMBL21253275 | 0.77 | ALDH1A1 (0.39) | ALDH1A1TSHRTHRB | |
| SCHEMBL28209430 | 0.77 | TSHR (0.45) | ALDH1A1TSHRTHRB | |
| SCHEMBL27415907 | 0.77 | TSHR (0.38) | ALDH1A1TSHRTHRB | |
| SCHEMBL5308928 | 0.76 | TSHR (0.35) | ALDH1A1TSHRTHRB | |
| SCHEMBL136874 | 0.76 | ALDH1A1 (0.38) | ALDH1A1TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8822213-B2 | Bispecific intracellular delivery vehicles | UNIVERSITY OF WASHINGTON (US) | 2014-09-02 | — | — | US | disclosed |
| US-20110281354-A1 | BISPECIFIC INTRACELLULAR DELIVERY VEHICLES | PHASERX, INC. (US) | 2011-11-17 | — | — | US | disclosed |