Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766204 | 0.90 | FFAR1 (0.43) | PTGS2FFAR1FFAR4PPARDCACNA1C | |
| SCHEMBL12823334 | 0.89 | MEN1 (0.42) | PTGS2FFAR1FFAR4APPCYP2C19 | |
| SCHEMBL13586556 | 0.88 | FFAR1 (0.35) | PTGS2FFAR1FFAR4PPARDACACA | |
| SCHEMBL12823278 | 0.88 | FFAR1 (0.35) | PTGS2FFAR1FFAR4PPARDACACA | |
| SCHEMBL12823432 | 0.88 | CYP2D6 (0.38) | PTGS2APPCYP2C19ACACAMAOB | |
| SCHEMBL12821157 | 0.87 | PTGS2 (0.43) | PTGS2FFAR1FFAR4APPCYP2C19 | |
| SCHEMBL12821219 | 0.86 | CA4 (0.36) | PTGS2FFAR1FFAR4APPCYP2C19 | |
| SCHEMBL12737131 | 0.85 | FFAR1 (0.42) | PTGS2FFAR1FFAR4PPARDCACNA1C | |
| SCHEMBL12737132 | 0.85 | FFAR1 (0.43) | FFAR1FFAR4PPARDCACNA1CMAOB | |
| SCHEMBL12822089 | 0.85 | LMNA (0.45) | FFAR1FFAR4APPCYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150966-A1 | TETRACYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT | チッソ株式会社 (JP) | 2009-12-17 | — | — | WO | disclosed |