SCHEMBL1358629

SCHEMBL1358629

O=C1CCCCCN1CO

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
TSHR P16473 3/20 0.48
HRH3 Q9Y5N1 1/20 0.47
CHRM2 P08172 3/20 0.46
CHRM5 P08912 3/20 0.46
CHRM1 P11229 3/20 0.46
CHRM3 P20309 3/20 0.46
CHRM4 P08173 2/20 0.46
CYP2D6 P10635 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
PIK3CD O00329 1/20 0.45
GAA P10253 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
PER2 O15055 2/20 0.41
ALDH1A1 P00352 2/20 0.40
BLM P54132 1/20 0.40
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11473243 1.00 KMT2A (0.52) KMT2AL3MBTL1TSHRHRH3CHRM2
SCHEMBL11475147 1.00 KMT2A (0.52) KMT2AL3MBTL1TSHRHRH3CHRM2
SCHEMBL1856822 0.98
SCHEMBL477750 0.91
SCHEMBL2790863 0.83 KMT2A (0.49) KMT2AL3MBTL1TSHRHRH3CHRM2
SCHEMBL3834112 0.81 KMT2A (0.60) KMT2AL3MBTL1TSHRHRH3CHRM2
SCHEMBL28796667 0.81 KMT2A (0.47) KMT2AL3MBTL1TSHRHRH3CHRM2
SCHEMBL7378056 0.80
SCHEMBL781813 0.80 TSHR (0.47) KMT2AL3MBTL1TSHRHRH3CHRM2
SCHEMBL8538164 0.79 KMT2A (0.46) KMT2AL3MBTL1TSHRHRH3CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109337097-B Solvent and method for preparing cellulose solution by using same 绍兴美标纺织品检验有限公司 2021-10-01 CN claimed
CN-104151221-A Synthesis method of bis(caproylaminomethyl)-thiourea YANTAI HENGDIKE ENERGY TECHNOLOGY CO LTD 2014-11-19 CN claimed
US-20110277844-A1 POLYMERS DERIVED FROM N-VINYL FORMAMIDE, VINYL AMIDES OR ACRYLAMIDES, AND REACTION SOLVENT, AND THE USES THEREOF HERCULES LLC 2011-11-17 US claimed
US-6605670-B1 Vulcanizable material comprising rubber with methylene donor and low molecular weight reaction product of polyhydric phenol, aromatic olefin and n-methylol lactam; low fuming INDSPEC CHEMICAL CORPORATION 2003-08-12 US claimed
US-6271300-B1 RESIN LATEX FOR BINDERS, EMULSIFIERS IN WATER, VINYL POLYMER SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2001-08-07 US claimed
US-6143884-A MIXING TOGETHER CELLULOSE AND POLYMERIZATION ANTI-DECAY ADDITIVE, WATER, AND SOLVENT MIXTURE OF N-METHYLMORPHOLINE OXIDE AND N-METHYLOLCAPROLACTAM TO FORM SLURRY; EVAPORATING WATER USING FILM TYPE EVAPORATOR ACELON CHEMICALS & FIBER CORPORATION (TW) 2000-11-07 US claimed
US-5929228-A Cellulose solution with low viscosity and process of preparing the same CHENG MENG-SONG (TW) 1999-07-27 US claimed
US-4769454-A Process for the preparation of N-methylol-caprolactam BAYER AKTIENGESELLSCHAFT (DE) 1988-09-06 US claimed
EP-0275551-A1 Process for the preparation of N-methylol caprolactam BAYER AG (DE) 1988-07-27 EP claimed
US-4187356-A Condensation of formaldehyde hydrate to form mixtures which, together with monomers capable of aminoplast formation are useful in the preparation of polyurethane foams BAYER AKTIENGESELLSCHAFT (DE) 1980-02-05 US claimed
US-3931112-A POLYURETHANE BAYER AKTIENGESELLSCHAFT (DT) 1976-01-06 US claimed
JP-11323655-A None JP disclosed
US-12497478-B2 High molecular weight block copolymers comprising repeating units derived from monomers comprising lactam and acryloyl moieties and hydrophilic monomers, compositions, and applications thereof ISP INVESTMENTS LLC (US) 2025-12-16 US disclosed
WO-2025024325-A2 ALL-ACRYLIC TRIBLOCK AND TETRABLOCK COPOLYMERS HAVING A LACTAM MOIETY AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2025-01-30 WO disclosed
US-20250032398-A1 HIGH MOLECULAR WEIGHT BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES AND HYDROPHILIC MONOMERS, COMPOSITIONS, AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2025-01-30 US disclosed
US-4128558-A FIREPROOFING BAYER AKTIENGESELLSCHAFT (DE) 1978-12-05 US disclosed
US-4008222-A POLYESTERS BAYER AKTIENGESELLSCHAFT (DT) 1977-02-15 US disclosed
US-3980677-A Anthraquinone dyestuffs containing sulphonic acid groups BAYER AKTIENGESELLSCHAFT (DT) 1976-09-14 US disclosed
US-3968104-A SOLVENTS BAYER AKTIENGESELLSCHAFT (DT) 1976-07-06 US disclosed
US-3931112-A POLYURETHANE BAYER AKTIENGESELLSCHAFT (DT) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12497478-B2 High molecular weight block copolymers comprising repeating units derived from monomers comprising lactam and acryloyl moieties and hydrophilic monomers, compositions, and applications thereof MRPL9, PRMT9, MRPL19 KMT2A 2553/4885L3MBTL1 598/4885TSHR 1038/4885
US-20250032398-A1 HIGH MOLECULAR WEIGHT BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES AND HYDROPHILIC MONOMERS, COMPOSITIONS, AND APPLICATIONS THEREOF PCNA, ADSL, APH1B KMT2A 4114/4885L3MBTL1 2847/4885TSHR 3587/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.