Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12821152 | 0.89 | BRD4 (0.34) | BRD4 | |
| SCHEMBL12718531 | 0.88 | BRD4 (0.33) | BRD4 | |
| SCHEMBL12908029 | 0.86 | BRD4 (0.37) | BRD4 | |
| SCHEMBL12822179 | 0.85 | NPC1 (0.33) | NPC1TP53PKMRAB9ASMN1; SMN2 | |
| SCHEMBL12718404 | 0.84 | RAB9A (0.38) | NPC1TP53PKMRAB9ASMN1; SMN2 | |
| SCHEMBL12822756 | 0.83 | BRD4 (0.34) | BRD4 | |
| SCHEMBL12907077 | 0.81 | CTSL (0.34) | BRD4 | |
| SCHEMBL12907009 | 0.81 | BRD4 (0.39) | BRD4 | |
| SCHEMBL12738874 | 0.81 | RARB (0.41) | NPC1TP53PKMRAB9ASMN1; SMN2 | |
| SCHEMBL13586484 | 0.81 | ALOX5AP (0.36) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150966-A1 | TETRACYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT | チッソ株式会社 (JP) | 2009-12-17 | — | — | WO | disclosed |