Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.59 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KDM5A | P29375 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14624528 | 0.86 | EPHX1 (0.74) | EPHX1DRD4MEN1KMT2AHPGD | |
| SCHEMBL13003422 | 0.81 | DRD4 (0.58) | EPHX1DRD4MCHR1SMN1; SMN2HRH3 | |
| SCHEMBL24011381 | 0.81 | EPHX1 (0.57) | EPHX1DRD4MEN1KMT2AMCHR1 | |
| SCHEMBL4981939 | 0.78 | EPHX1 (0.71) | EPHX1DRD4MEN1KMT2AMCHR1 | |
| SCHEMBL13003424 | 0.78 | CCR1 (0.45) | SMYD3EPHX2 | |
| SCHEMBL24011708 | 0.77 | EPHX1 (0.53) | EPHX1DRD4MEN1KMT2AMCHR1 | |
| SCHEMBL24011707 | 0.77 | EPHX1 (0.53) | EPHX1DRD4MEN1KMT2AMCHR1 | |
| SCHEMBL24011500 | 0.77 | EPHX1 (0.53) | EPHX1DRD4MEN1KMT2AMCHR1 | |
| SCHEMBL24011081 | 0.76 | RAB9A (0.59) | EPHX1MEN1KMT2AMCHR1EPHX2 | |
| SCHEMBL24011424 | 0.76 | EPHX1 (0.59) | EPHX1DRD4MEN1KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902046-B1 | PIPERIDINE DERIVATIVES USEFUL AS HISTAMINE H3 ANTAGONISTS | SCHERING CORP (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2007001975-A1 | PIPERIDINE DERIVATIVES USEFUL AS HISTAMINE H3 ANTAGONISTS | SCHERING CORPORATION (US) | 2007-01-04 | — | — | WO | disclosed |