SCHEMBL13589232

SCHEMBL13589232

CC(C)(c1ccc(-n2c3ccccc3c3ccccc32)cc1)c1ccc(C(C)(C)c2ccc(-n3c4ccccc4c4ccccc43)cc2)nc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.43
ATM Q13315 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
PIK3CD O00329 1/20 0.35
PIK3CA P42336 1/20 0.35
MTOR P42345 1/20 0.35
PIK3CG P48736 1/20 0.35
PPARG P37231 4/20 0.32
NR3C2 P08235 1/20 0.32
PPARA Q07869 2/20 0.32
KIF11 P52732 1/20 0.31
ALDH1A1 P00352 2/20 0.31
ESR1 P03372 1/20 0.31
CYP3A4 P08684 1/20 0.31
ESR2 Q92731 1/20 0.31
LIG1 P18858 1/20 0.31
GPR3 P46089 1/20 0.31
PTPN1 P18031 2/20 0.30
CYP11B1 P15538 1/20 0.30
CYP11B2 P19099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13589230 0.90 KDM4E (0.47) KDM4EATML3MBTL1PIK3CDPIK3CA
SCHEMBL10039116 0.84 KDM4E (0.59) KDM4EATML3MBTL1PPARGPPARA
SCHEMBL10100856 0.84 KDM4E (0.59) KDM4EATML3MBTL1PPARGPPARA
SCHEMBL19836759 0.81 KDM4E (0.61) KDM4EATML3MBTL1PPARGNR3C2
SCHEMBL16482566 0.80 KDM4E (0.53) KDM4EATML3MBTL1PPARGPPARA
SCHEMBL19933564 0.79 L3MBTL1 (0.52) KDM4EATML3MBTL1PPARGPPARA
SCHEMBL12011958 0.78 MAOA (0.47) KDM4EATML3MBTL1PIK3CDPIK3CA
SCHEMBL12241437 0.78 MAOA (0.47) KDM4EATML3MBTL1PIK3CDPIK3CA
SCHEMBL15695210 0.77 KDM4E (0.43) KDM4EATML3MBTL1PIK3CDPIK3CA
SCHEMBL9968239 0.77 PPARG (0.37) KDM4EATML3MBTL1PIK3CDPIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7629060-B2 Liquid crystal cells; durability, stability; brightness ; containing carbazole compound KONICA MINOLTA HOLDINGS, INC. (JP) 2009-12-08 US disclosed
US-7629060-B2 Liquid crystal cells; durability, stability; brightness ; containing carbazole compound KONICA MINOLTA HOLDINGS, INC. (JP) 2009-12-08 US disclosed