SCHEMBL1359080

SCHEMBL1359080

CCCCC1(CO)NC1=O

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.39
KDM4E B2RXH2 2/20 0.38
PKM P14618 2/20 0.38
HSD17B10 Q99714 1/20 0.35
SIRT2 Q8IXJ6 1/20 0.33
CYP19A1 P11511 1/20 0.33
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1983588 0.88 TDP1 (0.36) GAAKDM4EPKM
SCHEMBL10664843 0.85 ALDH1A1 (0.40) GAAKDM4EPKMHSD17B10CYP19A1
SCHEMBL10659897 0.85 CYP19A1 (0.35) GAAKDM4EPKMHSD17B10CYP19A1
SCHEMBL10665792 0.83 SMN1; SMN2 (0.42) GAAHSD17B10CYP19A1LMNA
SCHEMBL29775979 0.82 HSD17B10 (0.37) KDM4EPKMHSD17B10CYP19A1LMNA
SCHEMBL9895106 0.78 CYP19A1 (0.36) KDM4EPKMHSD17B10CYP19A1
SCHEMBL6331007 0.74 TDP1 (0.40) HSD17B10CYP19A1LMNA
SCHEMBL23367315 0.71 HSD17B10 (0.32) KDM4EPKMHSD17B10CYP19A1
SCHEMBL6692266 0.71 LMNA (0.40) KDM4ELMNA
SCHEMBL6695687 0.71 PDE7A (0.41) CYP19A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2346909-B1 POLYMERS DERIVED FROM N-VINYL FORMAMIDE, VINYL AMIDES OR ACRYLAMIDES, AND REACTION SOLVENT, AND THE USES THEREOF ISP INVESTMENTS INC (US) 2018-05-16 EP claimed
CN-109153933-A CARBON DIOXIDE CO-FLUID 艾默生环境优化技术有限公司 2019-01-04 CN disclosed
EP-2346909-B1 POLYMERS DERIVED FROM N-VINYL FORMAMIDE, VINYL AMIDES OR ACRYLAMIDES, AND REACTION SOLVENT, AND THE USES THEREOF ISP INVESTMENTS INC (US) 2018-05-16 EP disclosed
US-20110277844-A1 POLYMERS DERIVED FROM N-VINYL FORMAMIDE, VINYL AMIDES OR ACRYLAMIDES, AND REACTION SOLVENT, AND THE USES THEREOF HERCULES LLC 2011-11-17 US disclosed
EP-2346909-A1 POLYMERS DERIVED FROM N-VINYL FORMAMIDE, VINYL AMIDES OR ACRYLAMIDES, AND REACTION SOLVENT, AND THE USES THEREOF Isp Investments Inc. (US) 2011-07-27 EP disclosed
WO-2010056934-A1 POLYMERS DERIVED FROM N-VINYL FORMAMIDE, VINYL AMIDES OR ACRYLAMIDES, AND REACTION SOLVENT, AND THE USES THEREOF ISP INVESTMENTS INC. (US) 2010-05-20 WO disclosed