Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | MITF | O75030 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | CDC25A | P30304 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13171882 | 0.95 | MEN1 (0.52) | MAPTSMN1; SMN2MEN1KMT2ATHRB | |
| SCHEMBL10448839 | 0.94 | MEN1 (0.54) | MAPTSMN1; SMN2MEN1KMT2ATHRB | |
| SCHEMBL10086948 | 0.83 | ALDH1A1 (0.41) | MAPTSMN1; SMN2MEN1KMT2ATHRB | |
| SCHEMBL13642931 | 0.80 | MAPT (0.35) | MAPTSMN1; SMN2MEN1KMT2ATHRB | |
| SCHEMBL10448838 | 0.75 | MEN1 (0.54) | MAPTSMN1; SMN2MEN1KMT2ATHRB | |
| SCHEMBL10105233 | 0.73 | NPC1 (0.38) | MAPTSMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL16867589 | 0.71 | MEN1 (0.47) | MAPTSMN1; SMN2MEN1KMT2ATHRB | |
| SCHEMBL16867556 | 0.71 | MEN1 (0.47) | MAPTSMN1; SMN2MEN1KMT2ATHRB | |
| SCHEMBL30725973 | 0.69 | MEN1 (0.63) | MAPTSMN1; SMN2MEN1KMT2ATHRB | |
| SCHEMBL29271993 | 0.69 | TDP1 (0.42) | MAPTSMN1; SMN2MEN1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8894976-B2 | Fluorescent membrane intercalating probes and methods for their use | PHANOS TECHNOLOGIES, INC. (US) | 2014-11-25 | — | — | US | disclosed |
| US-8894976-B2 | Fluorescent membrane intercalating probes and methods for their use | PHANOS TECHNOLOGIES, INC. (US) | 2014-11-25 | — | — | US | disclosed |
| EP-1957453-B1 | FLUORESCENT MEMBRANE INTERCALATING PROBES AND METHODS FOR THEIR USE | PHANOS TECH INC (US) | 2014-08-20 | — | — | EP | disclosed |
| US-20090304598-A1 | FLUORESCENT MEMBRANE INTERCALATING PROBES AND METHODS FOR THEIR USE | PHANOS TECHNOLOGIES, INC. (US) | 2009-12-10 | — | — | US | disclosed |
| US-20090304598-A1 | FLUORESCENT MEMBRANE INTERCALATING PROBES AND METHODS FOR THEIR USE | PHANOS TECHNOLOGIES, INC. (US) | 2009-12-10 | — | — | US | disclosed |
| WO-2007061768-A2 | FLUORESCENT MEMBRANE INTERCALATING PROBES AND METHODS FOR THEIR USE | PHANOS TECHNOLOGIES, INC. (US) | 2007-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090304598-A1 | FLUORESCENT MEMBRANE INTERCALATING PROBES AND METHODS FOR THEIR USE | TIMM44, SLC47A2, TIMM50 | MAPT 4259/4885SMN1; SMN2 4592/4885MEN1 2427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.