Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.55 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.40 |
| ▸ | RHEB | Q15382 | 4/20 | 0.39 |
| ▸ | FLT3 | P36888 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19332317 | 0.88 | DAO (0.52) | DAOHRH4FLT3KDM4EALDH1A1 | |
| SCHEMBL30310454 | 0.88 | DAO (0.52) | DAOHRH4FLT3KDM4EALDH1A1 | |
| SCHEMBL1883225 | 0.84 | ALOX15 (0.58) | DAOALOX15KDM4EALDH1A1LMNA | |
| SCHEMBL30193757 | 0.84 | ALOX15 (0.58) | DAOALOX15KDM4EALDH1A1LMNA | |
| SCHEMBL6161388 | 0.84 | DAO (0.58) | DAORHEBF7F3GRIN1 | |
| SCHEMBL29425136 | 0.84 | DAO (0.58) | DAORHEBF7F3GRIN1 | |
| SCHEMBL30310623 | 0.83 | DAO (0.56) | DAOHRH4RHEBFLT3F7 | |
| SCHEMBL25758815 | 0.79 | ALOX15 (0.58) | DAOHRH4RHEBALOX15KDM4E | |
| SCHEMBL24019771 | 0.76 | ALOX15 (0.58) | DAOHRH4ALOX15IDO1TDO2 | |
| SCHEMBL9233998 | 0.74 | DAO (0.54) | DAORHEBF7F3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1390029-B1 | PHENYLINDOLES FOR THE TREATMENT OF HIV | IDENIX CAYMAN LTD (KY) | 2009-12-16 | — | — | EP | disclosed |