Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 2/20 | 0.43 |
| ▸ | ALB | P02768 | 6/20 | 0.43 |
| ▸ | IL2 | P60568 | 6/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RHEB | Q15382 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24740396 | 0.86 | ALOX15 (0.57) | ALOX15MEN1KMT2ARCE1ALPL | |
| SCHEMBL25758817 | 0.83 | KMT2A (0.54) | ALOX15MEN1KMT2ARCE1KDM4E | |
| SCHEMBL24740346 | 0.82 | ALOX15 (0.59) | ALOX15MEN1KMT2ARCE1ALPL | |
| SCHEMBL30310454 | 0.82 | DAO (0.52) | DAOKDM4EALDH1A1HRH4 | |
| SCHEMBL19332317 | 0.82 | DAO (0.52) | DAOKDM4EALDH1A1HRH4 | |
| SCHEMBL24019771 | 0.81 | ALOX15 (0.58) | ALOX15DAOPYGLHRH4 | |
| SCHEMBL24019693 | 0.81 | ALB (0.60) | ALOX15DAOMEN1KMT2ARCE1 | |
| SCHEMBL24019957 | 0.80 | ALOX15 (0.52) | ALOX15ALPLALBIL2MAPT | |
| SCHEMBL13593176 | 0.79 | DAO (0.55) | ALOX15DAOMEN1KMT2ARXFP1 | |
| SCHEMBL25758821 | 0.79 | IDO1 (0.50) | ALOX15MEN1KMT2ARCE1ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212152-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. | 2023-07-06 | — | — | US | disclosed |
| US-20230212152-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212152-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | CTRL, CTSL, CTSV | ALOX15 1455/4885DAO 894/4885MEN1 4306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.