⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL8701960 | 0.97 | PNMT (0.56) | — | |
| SCHEMBL749569 | 0.89 | PNMT (0.54) | — | |
| SCHEMBL1468326 | 0.89 | PNMT (0.54) | — | |
| SCHEMBL18457177 | 0.88 | PNMT (0.48) | — | |
| SCHEMBL10182282 | 0.88 | TDP1 (0.48) | — | |
| SCHEMBL6192350 | 0.87 | PNMT (0.52) | — | |
| SCHEMBL21447111 | 0.87 | PNMT (0.52) | — | |
| SCHEMBL22910024 | 0.87 | PNMT (0.52) | — | |
| SCHEMBL18746500 | 0.87 | PNMT (0.52) | — | |
| Ammonia Solution, Strong SCHEMBL4733194 | 0.87 | PNMT (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 385 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021078217-A1 | TETRACENE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 中国科学院化学研究所 | 2021-04-29 | — | — | WO | claimed |
| CN-112694388-A | Naphthacene derivative and preparation method and application thereof | 中国科学院化学研究所 | 2021-04-23 | — | — | CN | claimed |
| US-12612360-B2 | Substituted 6,7-dihydro-5H-benzo[7]annulene compounds and their derivatives, processes for their preparation and therapeutic uses thereof | SANOFI (FR) | 2026-04-28 | — | — | US | disclosed |
| EP-3515892-B1 | COMPOUNDS AND METHODS FOR IDO AND TDO MODULATION, AND INDICATIONS THEREFOR | PLEXXIKON INC (US) | 2026-04-15 | — | — | EP | disclosed |
| EP-4667458-A1 | PHARMACEUTICAL COMPOSITION FOR TREATMENT OF CANCER, COMPRISING SOS1 INHIBITOR AND ANTICANCER DRUG | Kanaph Therapeutics Inc. (KR) | 2025-12-24 | — | — | EP | disclosed |
| EP-4642784-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS AS INHIBITORS OF NLRP3 | PTC Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| US-20250326765-A1 | PDE4B INHIBITOR AND USE THEREOF | XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2025-10-23 | — | — | US | disclosed |
| US-20250263426-A1 | PDE4B INHIBITOR AND USE THEREOF | XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2025-08-21 | — | — | US | disclosed |
| EP-4534540-A1 | PDE4B INHIBITOR AND USE THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2025-04-09 | — | — | EP | disclosed |
| WO-2025026270-A1 | BENZO NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE REGULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2025-02-06 | — | — | WO | disclosed |
| US-20240400518-A1 | SOS1 INHIBITOR AND USE THEREOF | CYRUS THERAPEUTICS INC. (KR) | 2024-12-05 | — | — | US | disclosed |
| US-5227536-A | PROCESS FOR PREPARING HYDROXYBENZOCYCLOBUTENES | THE DOW CHEMICAL COMPANY (US) | 1993-07-13 | — | — | US | disclosed |
| WO-1993006072-A1 | PROCESS FOR PREPARING HYDROXYBENZOCYCLOBUTENES | THE DOW CHEMICAL COMPANY (US) | 1993-04-01 | — | — | WO | disclosed |
| WO-1993006083-A1 | PROCESS FOR PREPARING AMINOBENZOCYCLOBUTENES | THE DOW CHEMICAL COMPANY (US) | 1993-04-01 | — | — | WO | disclosed |
| US-5196103-A | Dielectric polycyclobutarene layer, adhesion, metal carbide interface, sputtering | THE DOW CHEMICAL COMPANY (US) | 1993-03-23 | — | — | US | disclosed |
| US-5136069-A | Reacting with halogenated organic compound in presence of palladium complex catalyst and inorganic hydrogen halide acceptor | THE DOW CHEMICAL COMPANY (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0323536-A1 | Arylcyclobutene/dienophile copolymers | THE DOW CHEMICAL COMPANY (US) | 1989-07-12 | — | — | EP | disclosed |
| US-4783514-A | Polymeric monoarylcyclobutane compositions | THE DOW CHEMICAL COMPANY (US) | 1988-11-08 | — | — | US | disclosed |
| US-4730030-A | Arylcyclobutane/dienophile copolymer | THE DOW CHEMICAL COMPANY (US) | 1988-03-08 | — | — | US | disclosed |
| US-4724260-A | Unsaturated alkyl monoarylcyclobutane monomers | THE DOW CHEMICAL COMPANY (US) | 1988-02-09 | — | — | US | disclosed |