Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.56 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HSD17B3 | P37058 | 5/20 | 0.44 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13594 | 0.97 | — | — | |
| Ammonia Solution, Strong SCHEMBL4733194 | 0.90 | PNMT (0.52) | PNMTASIC3TDP1L3MBTL1HSD17B3 | |
| SCHEMBL749569 | 0.86 | PNMT (0.54) | PNMTASIC3TDP1L3MBTL1HSD17B3 | |
| SCHEMBL30406919 | 0.86 | PNMT (0.54) | PNMTASIC3TDP1L3MBTL1HSD17B3 | |
| SCHEMBL1468326 | 0.86 | PNMT (0.54) | PNMTASIC3TDP1L3MBTL1HSD17B3 | |
| SCHEMBL18457177 | 0.85 | PNMT (0.48) | PNMTASIC3TDP1L3MBTL1HSD17B3 | |
| SCHEMBL10182282 | 0.85 | TDP1 (0.48) | PNMTASIC3TDP1L3MBTL1HSD17B3 | |
| SCHEMBL6192350 | 0.84 | PNMT (0.52) | PNMTASIC3TDP1L3MBTL1HSD17B3 | |
| SCHEMBL21447111 | 0.84 | PNMT (0.52) | PNMTASIC3TDP1L3MBTL1HSD17B3 | |
| SCHEMBL22910024 | 0.84 | PNMT (0.52) | PNMTASIC3TDP1L3MBTL1HSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837726-A | Antifungal agents derived from aspergillus fumigatus | MILLENNIUM PHARMACEUTICALS, INC. (US) | 1998-11-17 | — | — | US | disclosed |
| US-4939279-A | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1990-07-03 | — | — | US | disclosed |