SCHEMBL135940

SCHEMBL135940

O=C1CNC(c2ccccc2)O1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.40
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
KDM4E B2RXH2 1/20 0.37
ADORA3 P0DMS8 1/20 0.37
AR P10275 1/20 0.37
CYP19A1 P11511 1/20 0.37
MAOB P27338 1/20 0.37
HSD17B10 Q99714 1/20 0.37
ABL1 P00519 1/20 0.37
RIN1 Q13671 1/20 0.37
ALDH1A1 P00352 1/20 0.36
PRCP P42785 1/20 0.36
TSHR P16473 1/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
CTRC Q99895 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6253800 0.90 MEN1 (0.32) CYP2C9CYP2C19
SCHEMBL5855954 0.79 SLC6A2 (0.40) KDM4EHSD17B10ALDH1A1
SCHEMBL249120 0.77 CYP2C9 (0.42) CA2CYP2C9CYP2C19KDM4EADORA3
SCHEMBL12525029 0.77 CYP2C9 (0.42) CA2CYP2C9CYP2C19KDM4EADORA3
SCHEMBL3706077 0.77 CYP2C9 (0.42) CA2CYP2C9CYP2C19KDM4EADORA3
SCHEMBL7306016 0.77 CYP2C9 (0.42) CA2CYP2C9CYP2C19KDM4EADORA3
SCHEMBL12524998 0.77 CYP2C9 (0.42) CA2CYP2C9CYP2C19KDM4EADORA3
SCHEMBL9360043 0.77 ALDH1A1 (0.37) ALDH1A1
SCHEMBL23841973 0.76 CYP2C9 (0.41) CA2CYP2C9CYP2C19KDM4EADORA3
SCHEMBL10448418 0.76 HTR2C (0.47) CYP2C19GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 507 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116120252-B Preparation method of ramipril key intermediate derivative 浙江工业大学 2024-10-29 CN claimed
CN-116120252-A Preparation method of ramipril key intermediate derivative 浙江工业大学 2023-05-16 CN claimed
WO-2002004020-A2 PATHOGEN RESISTANCE IN ORGANISMS MPB COLOGNE GMBH (DE) 2002-01-17 WO claimed
US-5911987-A NEWCASTLE DISEASE VIRUS DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES OFFENTLICHEN RECHTS (DE) 1999-06-15 US claimed
EP-0749487-A1 CELL SURFACE PROTEIN AND EFFECTOR CELL BONDING REAGENT Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) 1996-12-27 EP claimed
WO-1995024490-A1 CELL SURFACE PROTEIN AND EFFECTOR CELL BONDING REAGENT Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) 1995-09-14 WO claimed
EP-0367233-A2 Process for the preparation of 2-(2-thienyl)-ethylamine and derivatives thereof OCCIDENTAL CHEMICAL CORPORATION (US) 1990-05-09 EP claimed
US-4874876-A ACYLATING THIOPHENE, REDUCING, HYDROLYZING OCCIDENTAL CHEMICAL CORPORATION (US) 1989-10-17 US claimed
JP-2196784-A None JP disclosed
JP-8067657-A None JP disclosed
EP-4585264-A2 HUMAN CGRP RECEPTOR BINDING PROTEINS AMGEN INC. (US) 2025-07-16 EP disclosed
CN-113908268-B Use of antibodies in the preparation of a medicament for the treatment or prevention of migraine 美国安进公司 2025-06-10 CN disclosed
US-20250163160-A1 Human Antigen Binding Proteins That Bind Beta-Klotho, FGF Receptors and Complexes Thereof AMGEN INC. 2025-05-22 US disclosed
US-12297260-B2 DKK1 antibodies and methods of use AMGEN INC. (US) 2025-05-13 US disclosed
US-4874876-A ACYLATING THIOPHENE, REDUCING, HYDROLYZING OCCIDENTAL CHEMICAL CORPORATION (US) 1989-10-17 US disclosed
US-4469768-A Electrophotographic light-sensitive material comprising a charge-generating material and a charge-transporting material FUJI PHOTO FILM CO., LTD. (JP) 1984-09-04 US disclosed
US-4443461-A N-[2-[[1-[1H-Indolylalkyl- or oxoalkyl]-4-piperidinyl]-amino]-2-oxoethyl]-arylcarboxamide derivatives JOHN WYETH & BROTHER LIMITED (GB) 1984-04-17 US disclosed
US-4373100-A ANIMAL FEEDS EGYT GYOGYSZERVEGYESZETI GYAR (HU) 1983-02-08 US disclosed
US-3987185-A INGIBITS ANTIGEN-ANTIBODY REACTIONS IN ANIMALS RICHARDSON-MERRELL INC. (US) 1976-10-19 US disclosed
JP-H00867657-A 0001-01-01 JP disclosed