Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 18/20 | 0.54 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13594351 | 0.91 | F2R (0.51) | F2RF2 | |
| SCHEMBL4407483 | 0.87 | F2R (0.57) | F2RF2 | |
| SCHEMBL13594346 | 0.82 | F2R (0.52) | F2RF2 | |
| SCHEMBL13594350 | 0.81 | F2R (0.49) | F2RF2 | |
| SCHEMBL4405572 | 0.78 | F2R (0.55) | F2RF2 | |
| SCHEMBL8495526 | 0.78 | CTSL (0.54) | F2SIRT1 | |
| SCHEMBL8495706 | 0.78 | CTSL (0.54) | F2SIRT1 | |
| SCHEMBL26429562 | 0.76 | CTSL (0.55) | F2SIRT1 | |
| SCHEMBL1842451 | 0.76 | SIRT2 (0.46) | SIRT1 | |
| SCHEMBL29374941 | 0.76 | SIRT2 (0.46) | SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629319-B2 | Heteroaryl peptidomimetics as thrombin receptor antagonists | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-12-08 | — | — | US | disclosed |