Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.55 |
| ▸ | F2 | P00734 | 2/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.54 |
| ▸ | KDM1A | O60341 | 9/20 | 0.54 |
| ▸ | MAOA | P21397 | 7/20 | 0.54 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.54 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.53 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26430196 | 0.90 | SIRT5 (0.53) | SIRT5SIRT1SIRT2SIRT3 | |
| SCHEMBL2193250 | 0.88 | SSTR3 (0.57) | CTSLSIRT5F2PRSS1PRSS2 | |
| SCHEMBL8495706 | 0.88 | CTSL (0.54) | CTSLSIRT5F2PRSS1PRSS2 | |
| SCHEMBL8495526 | 0.88 | CTSL (0.54) | CTSLSIRT5F2PRSS1PRSS2 | |
| SCHEMBL5929274 | 0.86 | CTSL (0.73) | CTSLSIRT2 | |
| SCHEMBL3381295 | 0.86 | CTSL (0.64) | CTSLSIRT1SIRT2 | |
| SCHEMBL18831943 | 0.86 | SIRT5 (0.60) | SIRT5F2PRSS1PRSS2PRSS3 | |
| SCHEMBL18831940 | 0.86 | SIRT5 (0.60) | SIRT5F2PRSS1PRSS2PRSS3 | |
| SCHEMBL17289476 | 0.84 | SIRT5 (0.55) | SIRT5F2PRSS1PRSS2PRSS3 | |
| SCHEMBL1803249 | 0.84 | SIRT5 (0.54) | SIRT5SIRT1SIRT2SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022203930-A9 | FLUOROGENIC CYANINE CARBAMATES | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2023-04-27 | — | — | WO | disclosed |