Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 10/20 | 0.50 |
| ▸ | NPY4R | P50391 | 4/20 | 0.40 |
| ▸ | NPY1R | P25929 | 3/20 | 0.40 |
| ▸ | NPY2R | P49146 | 3/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.40 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.39 |
| ▸ | MC4R | P32245 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13594357 | 1.00 | F2R (0.50) | F2RNPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL13594343 | 0.89 | F2R (0.45) | F2RNPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL13594358 | 0.83 | F2R (0.44) | F2RKISS1R | |
| SCHEMBL4402395 | 0.82 | HASPIN (0.47) | F2R | |
| SCHEMBL4407483 | 0.81 | F2R (0.57) | F2R | |
| SCHEMBL4405572 | 0.77 | F2R (0.55) | F2R | |
| SCHEMBL10944144 | 0.76 | GNPAT (0.59) | NPY4RNPY1RNPY2RNPY5RKISS1R | |
| SCHEMBL13563435 | 0.71 | KISS1R (0.62) | NPY4RNPY1RNPY2RNPY5RKISS1R | |
| SCHEMBL12792618 | 0.71 | KISS1R (0.62) | NPY4RNPY1RNPY2RNPY5RKISS1R | |
| SCHEMBL30045851 | 0.70 | KISS1R (0.61) | NPY4RNPY1RNPY2RNPY5RKISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629319-B2 | Heteroaryl peptidomimetics as thrombin receptor antagonists | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-12-08 | — | — | US | disclosed |