Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 12/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13594357 | 0.83 | F2R (0.50) | F2RKISS1R | |
| SCHEMBL13594560 | 0.83 | F2R (0.50) | F2RKISS1R | |
| SCHEMBL13594343 | 0.74 | F2R (0.45) | F2R | |
| SCHEMBL4407483 | 0.73 | F2R (0.57) | F2R | |
| SCHEMBL4405572 | 0.69 | F2R (0.55) | F2RPTPN1 | |
| SCHEMBL4402395 | 0.69 | HASPIN (0.47) | F2RHASPINMTNR1AMTNR1B | |
| SCHEMBL10944144 | 0.67 | GNPAT (0.59) | KISS1RPTPN2PTPN1 | |
| SCHEMBL4399845 | 0.65 | CACNB4 (0.54) | F2R | |
| SCHEMBL14531809 | 0.64 | KISS1R (0.49) | MMP1MMP8KISS1RPTPN2PTPN1 | |
| SCHEMBL24915332 | 0.63 | GNPAT (0.55) | MMP1MMP3MMP8KISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629319-B2 | Heteroaryl peptidomimetics as thrombin receptor antagonists | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-12-08 | — | — | US | disclosed |
| US-7618945-B2 | Heteroaryl peptidomimetics as thrombin receptor antagonists | JANSSEN PHARMACEUTICA, N.V. (BE) | 2009-11-17 | — | — | US | disclosed |