Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 11/20 | 0.88 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | F3 | P13726 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13595492 | 0.94 | MIF (1.00) | MIFMAPTKMT2AALDH1A1GFER | |
| SCHEMBL13595484 | 0.94 | MIF (1.00) | MIFMAPTKMT2AALDH1A1GAA | |
| SCHEMBL4195699 | 0.92 | MIF (1.00) | MIFMAPTKMT2ANPC1 | |
| SCHEMBL4195701 | 0.92 | MIF (1.00) | MIFMAPTKMT2ANPC1 | |
| SCHEMBL14344696 | 0.80 | MIF (0.59) | MIFMAPTKMT2AALDH1A1GAA | |
| SCHEMBL14345061 | 0.80 | MIF (0.62) | MIFMAPTKMT2AALDH1A1GAA | |
| SCHEMBL11963969 | 0.79 | MIF (0.75) | MIFMAPTPLA2G7NPC1 | |
| SCHEMBL3221490 | 0.78 | MIF (0.76) | MIFMAPTKMT2APLA2G7NPC1 | |
| SCHEMBL3221487 | 0.78 | MIF (0.76) | MIFMAPTKMT2APLA2G7NPC1 | |
| SCHEMBL14345074 | 0.77 | MIF (0.63) | MIFMAPTKMT2AALDH1A1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318509-A1 | Oxime Derivatives as Inhibitors of Macrophage Migration Inhibitory Factor | FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH, THE | 2009-12-24 | — | — | US | disclosed |
| US-20090318509-A1 | Oxime Derivatives as Inhibitors of Macrophage Migration Inhibitory Factor | FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH, THE | 2009-12-24 | — | — | US | disclosed |
| WO-2007145888-A2 | OXIME DERIVATIVES AS INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR | THE FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH (US) | 2007-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318509-A1 | Oxime Derivatives as Inhibitors of Macrophage Migration Inhibitory Factor | MIF, MSR1, MMP12 | MIF 1/4885MAPT 4762/4885KMT2A 3719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.