Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 10/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4195699 | 1.00 | MIF (1.00) | MIFKMT2AMAPTPKMRAB9A | |
| SCHEMBL13595484 | 0.98 | MIF (1.00) | MIFKMT2AMAPTPKMRAB9A | |
| SCHEMBL13595492 | 0.95 | MIF (1.00) | MIFKMT2AMAPTRAB9A | |
| SCHEMBL13595486 | 0.92 | MIF (0.88) | MIFKMT2AMAPTNPC1 | |
| SCHEMBL3221487 | 0.86 | MIF (0.76) | MIFKMT2AMAPTPKMRAB9A | |
| SCHEMBL3221490 | 0.86 | MIF (0.76) | MIFKMT2AMAPTPKMRAB9A | |
| SCHEMBL11963969 | 0.84 | MIF (0.75) | MIFMAPTPKMRAB9APOLB | |
| SCHEMBL14345046 | 0.82 | MIF (0.69) | MIFKMT2AMAPTRAB9ASTS | |
| SCHEMBL14344991 | 0.81 | MIF (0.67) | MIFKMT2AMAPTPKMRAB9A | |
| SCHEMBL13595476 | 0.81 | MIF (0.67) | MIFKMT2AMAPTPKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318509-A1 | Oxime Derivatives as Inhibitors of Macrophage Migration Inhibitory Factor | FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH, THE | 2009-12-24 | — | — | US | disclosed |
| EP-2023732-A2 | OXIME DERIVATIVES AS INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR | The Feinstein Institute for Medical Research (US) | 2009-02-18 | — | — | EP | disclosed |
| WO-2007145888-A2 | OXIME DERIVATIVES AS INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR | THE FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH (US) | 2007-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318509-A1 | Oxime Derivatives as Inhibitors of Macrophage Migration Inhibitory Factor | MIF, MSR1, MMP12 | MIF 1/4885KMT2A 3719/4885MAPT 4762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.