Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.45 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.45 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14038214 | 0.92 | NPC1 (0.41) | NPC1RAB9ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL27100252 | 0.81 | CYP3A4 (0.46) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL21701157 | 0.80 | CYP1A2 (0.43) | NPC1RAB9ASMN1; SMN2ALDH1A1PTGS2 | |
| SCHEMBL21701145 | 0.78 | CYP3A4 (0.51) | ALDH1A1LMNACYP2C9NFKB1TSHR | |
| SCHEMBL1941433 | 0.76 | CYP1A2 (0.53) | SMN1; SMN2ALDH1A1KMT2ALMNACYP2C9 | |
| SCHEMBL1941434 | 0.76 | CYP1A2 (0.53) | SMN1; SMN2ALDH1A1KMT2ALMNACYP2C9 | |
| SCHEMBL3856527 | 0.76 | CYP1A2 (0.53) | SMN1; SMN2ALDH1A1KMT2ALMNACYP2C9 | |
| SCHEMBL9372718 | 0.76 | PTGS1 (0.56) | CHRM1PDE4APTGS1PTGS2CXCR1 | |
| SCHEMBL23873712 | 0.75 | MAOA (0.48) | NPC1RAB9ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL27439818 | 0.75 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638654-B2 | 1-fluoro-1, 1-bis-(phenylsulfonyl)methane and production method thereof | NAGOYA INSTITUTE OF TECHNOLOGY (JP) | 2009-12-29 | — | — | US | disclosed |
| US-7638654-B2 | 1-fluoro-1, 1-bis-(phenylsulfonyl)methane and production method thereof | NAGOYA INSTITUTE OF TECHNOLOGY (JP) | 2009-12-29 | — | — | US | disclosed |
| US-20090131723-A1 | 1-Fluoro-1,1-Bis-(Phenylsulfonyl)Methane and Production Method Thereof | TOSOH F-TECH, INC. (JP) | 2009-05-21 | — | — | US | disclosed |
| US-20090131723-A1 | 1-Fluoro-1,1-Bis-(Phenylsulfonyl)Methane and Production Method Thereof | TOSOH F-TECH, INC. (JP) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131723-A1 | 1-Fluoro-1,1-Bis-(Phenylsulfonyl)Methane and Production Method Thereof | CYP2S1, ARSA, MSMO1 | NPC1 1423/4885RAB9A 1401/4885SMN1; SMN2 3149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.