Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1941433 | 1.00 | CYP1A2 (0.53) | CYP1A2ALDH1A1CYP3A4TDP1GLA | |
| SCHEMBL1941434 | 1.00 | CYP1A2 (0.53) | CYP1A2ALDH1A1CYP3A4TDP1GLA | |
| SCHEMBL3321163 | 0.86 | CYP1A2 (0.56) | CYP1A2ALDH1A1TDP1GLAHCAR2 | |
| SCHEMBL3321160 | 0.86 | CYP1A2 (0.56) | CYP1A2ALDH1A1TDP1GLAHCAR2 | |
| SCHEMBL3321162 | 0.86 | CYP1A2 (0.56) | CYP1A2ALDH1A1TDP1GLAHCAR2 | |
| SCHEMBL24667207 | 0.84 | CYP1A2 (0.47) | CYP1A2ALDH1A1CYP3A4TDP1GLA | |
| SCHEMBL27713535 | 0.84 | CYP1A2 (0.47) | CYP1A2ALDH1A1CYP3A4TDP1GLA | |
| SCHEMBL7097856 | 0.82 | TDP1 (0.52) | CYP1A2ALDH1A1CYP3A4TDP1GLA | |
| SCHEMBL1199677 | 0.82 | TDP1 (0.52) | CYP1A2ALDH1A1CYP3A4TDP1GLA | |
| SCHEMBL27100252 | 0.82 | CYP3A4 (0.46) | ALDH1A1CYP3A4LMNAMAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030162994-A1 | 6,6'-Bis-(1-Phosphanorbornadiene) diphosphines, their preparation and their uses | MATHEY FRANCOIS (FR) | 2003-08-28 | — | — | US | claimed |
| US-20020042540-A1 | New 6,6'-bis-(1-phosphanorbornadiene) diphosphines, their preparation and their uses | MATHEY FRANCOIS (FR) | 2002-04-11 | — | — | US | claimed |
| US-7589196-B2 | Amine-substituted biphenyldiphosphines | SOLVIAS AG (CH) | 2009-09-15 | — | — | US | disclosed |
| US-7375241-B2 | Ferrocenyl-1,2-diphosphines, the production thereof and their use | SOLVIAS A.G. (CH) | 2008-05-20 | — | — | US | disclosed |
| EP-1658298-B1 | PHOSPHORUS-CONTAINING IMIDAZOLINES AND METAL COMPLEXES THEREOF | SOLVIAS AG (CH) | 2008-03-26 | — | — | EP | disclosed |
| EP-1692151-B1 | FERROCENYL-1, 2-DIPHOSPHINES, THE PRODUCTION THEREOF AND THEIR USE | SOLVIAS AG (CH) | 2007-09-12 | — | — | EP | disclosed |
| US-20070142655-A1 | Ferrocenyl-1,2-diphosphines, the production thereof and their use | SOLVIAS AG (CH) | 2007-06-21 | — | — | US | disclosed |
| US-20070010493-A1 | Phospinite-imidazolines and metal complexes thereof | SOLVIAS AG (CH) | 2007-01-11 | — | — | US | disclosed |
| US-20060276643-A1 | Amine-substituted diphenyldiphosphines | FAURECIA SYSTEMES D'ECHAPPEMENT (FR) | 2006-12-07 | — | — | US | disclosed |
| EP-1692151-A1 | FERROCENYL-1, 2-DIPHOSPHINES, THE PRODUCTION THEREOF AND THEIR USE | Solvias AG (CH) | 2006-08-23 | — | — | EP | disclosed |
| EP-1296994-B1 | FERROCENYL DIPHOSPHINES AND THEIR USE | SOLVIAS AG (CH) | 2005-12-07 | — | — | EP | disclosed |
| US-20020062027-A1 | Phosphinite-oxazolines and metal complexes | SOLVIAS AG (CH) | 2002-05-23 | — | — | US | disclosed |
| US-20020042540-A1 | New 6,6'-bis-(1-phosphanorbornadiene) diphosphines, their preparation and their uses | MATHEY FRANCOIS (FR) | 2002-04-11 | — | — | US | disclosed |
| EP-1191030-A2 | Phosphinite-oxazolines and metal complexes | Solvias AG (CH) | 2002-03-27 | — | — | EP | disclosed |
| WO-2002002578-A1 | FERROCENYL DIPHOSPHINES AND THEIR USE | SOLVIAS AG (CH) | 2002-01-10 | — | — | WO | disclosed |
| EP-1155024-A1 | CHIRAL DIAZAPHOSPHOLIDINE LIGANDS | The University of Warwick (GB) | 2001-11-21 | — | — | EP | disclosed |
| US-6288279-B1 | THEIR PREPARATION PROCESS AND THEIR USE IN ASYMMETRICAL CATALYSIS. REARRANGING A DIPHOSPHOLE, REACTING THE DIPHOSPHOLE WITH AN ACETYLENIC COMPOUND TO FORM THE DIPHOSPHINE | RHODIA CHIMIE (FR) | 2001-09-11 | — | — | US | disclosed |
| WO-2000050430-A1 | CHIRAL DIAZAPHOSPHOLIDINE LIGANDS | THE UNIVERSITY OF WARWICK (GB) | 2000-08-31 | — | — | WO | disclosed |
| EP-0968220-A1 | 6,6'-BIS-(1-PHOSPHANORBORNADIENE) DIPHOSPHINES | RHODIA CHIMIE (FR) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998039345-A1 | 6,6'-BIS-(1-PHOSPHANORBORNADIENE) DIPHOSPHINES | RHODIA CHIMIE (FR) | 1998-09-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276643-A1 | Amine-substituted diphenyldiphosphines | DDC, PNMT, DDT | CYP1A2 239/4885ALDH1A1 389/4885CYP3A4 323/4885 |
| US-20070142655-A1 | Ferrocenyl-1,2-diphosphines, the production thereof and their use | PHOSPHO1, INPP5B, PPA1 | CYP1A2 2139/4885ALDH1A1 2167/4885CYP3A4 2821/4885 |
| US-20020062027-A1 | Phosphinite-oxazolines and metal complexes | OXER1, OXGR1, H1-4 | CYP1A2 791/4885ALDH1A1 661/4885CYP3A4 452/4885 |
| US-20070010493-A1 | Phospinite-imidazolines and metal complexes thereof | H1-0, H1-2, H1-3 | CYP1A2 610/4885ALDH1A1 2937/4885CYP3A4 606/4885 |
| US-20020042540-A1 | New 6,6'-bis-(1-phosphanorbornadiene) diphosphines, their preparation and their uses | PHOSPHO1, DUS2, DCPS | CYP1A2 545/4885ALDH1A1 1460/4885CYP3A4 867/4885 |
| US-20030162994-A1 | 6,6'-Bis-(1-Phosphanorbornadiene) diphosphines, their preparation and their uses | DUS2, PHOSPHO1, DCPS | CYP1A2 303/4885ALDH1A1 1115/4885CYP3A4 660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.