Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13841091 | 0.86 | KDM4E (0.38) | ALDH1A1HTTMEN1KMT2APOLB | |
| SCHEMBL13596040 | 0.84 | HTT (0.38) | ALDH1A1HTTMEN1KMT2AHCRTR1 | |
| SCHEMBL13841092 | 0.81 | ALDH1A1 (0.41) | ALDH1A1HTTMEN1KMT2AHCRTR1 | |
| SCHEMBL3955829 | 0.81 | ALDH1A1 (0.50) | ALDH1A1HTTMEN1KMT2APOLB | |
| SCHEMBL7606859 | 0.78 | ALDH1A1 (0.46) | ALDH1A1POLBHCRTR1HCRTR2MAPT | |
| SCHEMBL13841089 | 0.77 | LMNA (0.35) | ALDH1A1HTTMEN1KMT2AHCRTR1 | |
| SCHEMBL12646517 | 0.76 | EDNRA (0.41) | ALDH1A1HTTHCRTR1HCRTR2MAPT | |
| SCHEMBL1278957 | 0.72 | ALDH1A1 (0.41) | ALDH1A1KDM4EBRD4L3MBTL1 | |
| SCHEMBL4126911 | 0.72 | — | — | |
| SCHEMBL6993519 | 0.71 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318690-A1 | Benzisoxazole Compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318690-A1 | Benzisoxazole Compound | NR1I2, NR1I3, NR0B1 | ALDH1A1 858/4885HTT 3905/4885MEN1 1361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.